A panoramic review of IL-6: Structure, pathophysiological roles and inhibitors
Abstract Interleukin-6 (IL-6) is a pleiotropic pro-inflammatory cytokine. Its deregulation is
associated with chronic inflammation, and multifactorial auto-immune disorders. It mediates …
associated with chronic inflammation, and multifactorial auto-immune disorders. It mediates …
[HTML][HTML] SOCS proteins in immunity, inflammatory diseases, and immune-related cancer
Cytokine signaling represents one of the cornerstones of the immune system, mediating the
complex responses required to facilitate appropriate immune cell development and function …
complex responses required to facilitate appropriate immune cell development and function …
[HTML][HTML] Exercise-induced changes in visceral adipose tissue mass are regulated by IL-6 signaling: a randomized controlled trial
AS Wedell-Neergaard, LL Lehrskov, RH Christensen… - Cell metabolism, 2019 - cell.com
Visceral adipose tissue is harmful to metabolic health. Exercise training reduces visceral
adipose tissue mass, but the underlying mechanisms are not known. Interleukin-6 (IL-6) …
adipose tissue mass, but the underlying mechanisms are not known. Interleukin-6 (IL-6) …
[HTML][HTML] Role of interleukins in the pathogenesis of pulmonary fibrosis
YX She, QY Yu, XX Tang - Cell Death Discovery, 2021 - nature.com
Interleukins, a group of cytokines participating in inflammation and immune response, are
proved to be involved in the formation and development of pulmonary fibrosis. In this article …
proved to be involved in the formation and development of pulmonary fibrosis. In this article …
[HTML][HTML] Interleukin-6: a novel target for cardio-cerebrovascular diseases
JH Su, MY Luo, N Liang, SX Gong, W Chen… - Frontiers in …, 2021 - frontiersin.org
Cardio-Cerebrovascular Disease is a collective term for cardiovascular disease and
cerebrovascular disease, being a serious threat to human health. A growing number of …
cerebrovascular disease, being a serious threat to human health. A growing number of …
The role of IL-6 and IL-6 blockade in COVID-19
N Potere, A Batticciotto, A Vecchié… - Expert review of …, 2021 - Taylor & Francis
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …
[HTML][HTML] Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles
S Qian, O Golubnitschaja, X Zhan - Epma Journal, 2019 - Springer
A strong relationship exists between tumor and inflammation, which is the hot point in cancer
research. Inflammation can promote the occurrence and development of cancer by …
research. Inflammation can promote the occurrence and development of cancer by …
[HTML][HTML] The role of interleukin-6 family members in cardiovascular diseases
Y Feng, D Ye, Z Wang, H Pan, X Lu, M Wang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular disease is one of the main causes of human mortality. Cytokines play crucial
roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a …
roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a …
[HTML][HTML] The relation between trace element status (zinc, copper, magnesium) and clinical outcomes in COVID-19 infection during pregnancy
SARS CoV-2 is a novel coronavirus which has caused many deaths in the recent pandemic.
This study aimed to determine zinc, copper and magnesium status on pregnant women with …
This study aimed to determine zinc, copper and magnesium status on pregnant women with …
Role and therapeutic potential of melatonin in various type of cancers
S Gurunathan, M Qasim, MH Kang… - OncoTargets and …, 2021 - Taylor & Francis
Cancer is a large group of diseases and the second leading cause of death worldwide.
Lung, prostate, colorectal, stomach, and liver cancers are the most common types of cancer …
Lung, prostate, colorectal, stomach, and liver cancers are the most common types of cancer …