Adaptive immunity
FA Bonilla, HC Oettgen - Journal of Allergy and Clinical Immunology, 2010 - Elsevier
The innate immune system provides critical mechanisms for the rapid sensing and
elimination of pathogens. Adaptive immunity has evolved to provide a broader and more …
elimination of pathogens. Adaptive immunity has evolved to provide a broader and more …
The genetics and epigenetics of atopic dermatitis—filaggrin and other polymorphisms
Y Liang, C Chang, Q Lu - Clinical reviews in allergy & immunology, 2016 - Springer
Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by a combination of
genetic and environmental factors. Genetic evidences depict a complex network comprising …
genetic and environmental factors. Genetic evidences depict a complex network comprising …
Genetic and epigenetic aspects of atopic dermatitis
B Nedoszytko, E Reszka, D Gutowska-Owsiak… - International journal of …, 2020 - mdpi.com
Atopic dermatitis is a heterogeneous disease, in which the pathogenesis is associated with
mutations in genes encoding epidermal structural proteins, barrier enzymes, and their …
mutations in genes encoding epidermal structural proteins, barrier enzymes, and their …
Both inflammatory and regulatory cytokine responses to malaria are blunted with increasing age in highly exposed children
Background Young children are at greatest risk for malaria-associated morbidity and
mortality. The immune response of young children differs in fundamental ways from that of …
mortality. The immune response of young children differs in fundamental ways from that of …
The association between diabetes and obesity with Dengue infections
SD Sekaran, ZM Liew, HC Yam, CS Raju - Diabetology & Metabolic …, 2022 - Springer
Dengue, an arboviral disease is a global threat to public health as the number of Dengue
cases increases through the decades and this trend is predicted to continue. Non …
cases increases through the decades and this trend is predicted to continue. Non …
In utero priming of highly functional effector T cell responses to human malaria
PM Odorizzi, P Jagannathan, TI McIntyre… - Science translational …, 2018 - science.org
Malaria remains a significant cause of morbidity and mortality worldwide, particularly in
infants and children. Some studies have reported that exposure to malaria antigens in utero …
infants and children. Some studies have reported that exposure to malaria antigens in utero …
Genomic, Epigenomic, Transcriptomic, Proteomic and Metabolomic Approaches in Atopic Dermatitis
Atopic dermatitis (AD) is a chronic inflammatory skin disease with a high prevalence in the
developed countries. It is associated with atopic and non-atopic diseases, and its close …
developed countries. It is associated with atopic and non-atopic diseases, and its close …
Epigenetics in immune development and in allergic and autoimmune diseases
Epigenetic mechanisms such as DNA methylation, histone modification, and micro RNA
signaling regulate the activity of the genome. Virtually all aspects of immunity involve some …
signaling regulate the activity of the genome. Virtually all aspects of immunity involve some …
The association between IFN-γ and IL-4 genetic polymorphisms and childhood susceptibility to bronchial asthma
HR Huang, YQ Zhong, JF Wu - Gene, 2012 - Elsevier
The present study aims to investigate the association between the genetic polymorphisms of
interferon (IFN)-γ and interleukin (IL)-4 with childhood susceptibility to asthma and the levels …
interferon (IFN)-γ and interleukin (IL)-4 with childhood susceptibility to asthma and the levels …
Identification of biomarker sets for predicting the efficacy of sublingual immunotherapy against pollen-induced allergic rhinitis
M Gotoh, O Kaminuma, A Nakaya… - International …, 2017 - academic.oup.com
Sublingual immunotherapy (SLIT) is effective against allergic rhinitis, although a substantial
proportion of individuals is refractory. Herein, we describe a predictive modality to reliably …
proportion of individuals is refractory. Herein, we describe a predictive modality to reliably …