Oxidative stress and inflammation distinctly drive molecular mechanisms of diastolic dysfunction and remodeling in female and male heart failure with preserved …

S Zhazykbayeva, R Hassoun, M Herwig… - Frontiers in …, 2023 - frontiersin.org
Heart failure with preserved ejection fraction (HFpEF) is a complex cardiovascular
insufficiency syndrome presenting with an ejection fraction (EF) of greater than 50% along …

Unmasking of oestrogen‐dependent changes in left ventricular structure and function in aged female rats: a potential model for pre‐heart failure with preserved …

M Bustamante, A Garate‐Carrillo, B R. Ito… - The Journal of …, 2019 - Wiley Online Library
Key points Heart failure with preserved ejection fraction (HFpEF) is seen more frequently in
older women; risk factors include age, hypertension and excess weight. No female animal …

The moderating effect of fluid overload on the relationship between the augmentation index and left ventricular diastolic function in patients with CKD

BG Han, D Pak, JS Kim, Y Sohn - Scientific Reports, 2024 - nature.com
Increased vascular stiffness, fluid overload, and left ventricular diastolic dysfunction (LVDD)
are common in patients with chronic kidney disease (CKD). We investigated the potential …

Impact of pregnancy on the natural history of women with hypertrophic cardiomyopathy

C Fumagalli, C Zocchi, F Cappelli… - European Journal of …, 2024 - academic.oup.com
Aims Whether pregnancy is a modifier of the long-term course and outcome of women with
hypertrophic cardiomyopathy (HCM) is unknown. We assessed the association of pregnancy …

GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number

Z Zhao, H Wang, M Lin, L Groban - Biochemical and biophysical research …, 2015 - Elsevier
Chronic activation of the novel estrogen receptor GPR30 by its agonist G1 mitigates the
adverse effects of estrogen (E2) loss on cardiac structure and function. Using the …

Cardioprotection by low-dose of estrogen and testosterone at the physiological ratio on ovariectomized rats during ischemia/reperfusion injury

L Fu, Y Liu, J Wang, Y Sun, L Zhang, T Wu… - Journal of …, 2017 - journals.lww.com
Although estrogen and testosterone deficiency have often been associated with the
development of cardiac diseases in postmenopausal women, the benefits of estrogen or …

Left ventricular diastolic dysfunction in normotensive postmenopausal women with type 2 diabetes mellitus

M Maiello, A Zito, A Cecere, MM Ciccone… - Cardiology …, 2017 - journals.viamedica.pl
Background: The prevalence of heart failure among diabetic patients is high, also in those
with normal blood pressure and without coronary artery disease, even when …

Association of menopause age and N-terminal pro brain natriuretic peptide: the Multi-Ethnic Study of Atherosclerosis

IA Ebong, KE Watson, DC Goff Jr, DA Bluemke… - Menopause, 2015 - journals.lww.com
Objective Menopause age can affect the risk of developing cardiovascular disease (CVD).
The purpose of this study was to investigate the associations of early menopause …

Study on depletion of ovarian function and late‐life chronic diseases in India

S Kundu, SS Acharya - International Journal of Gynecology & …, 2023 - Wiley Online Library
Objective The current study aims to understand premature and early menopausal age in
association with chronic conditions. Methods The present cross‐sectional study analyzed …

High-normal diastolic blood pressure as a risk factor for left ventricular diastolic dysfunction in healthy postmenopausal women

M Kimura, H Sekiguchi, K Shimamoto… - Hypertension …, 2022 - nature.com
Left ventricular (LV) diastolic dysfunction is associated with heart failure with preserved
ejection fraction, and metabolic syndrome (MetS) is a risk factor. However, there is limited …