Brain neural patterns and the memory function of sleep

G Girardeau, V Lopes-dos-Santos - Science, 2021 - science.org
Sleep is crucial for healthy cognition, including memory. The two main phases of sleep, REM
(rapid eye movement) and non-REM sleep, are associated with characteristic …

The brain in motion: How ensemble fluidity drives memory-updating and flexibility

W Mau, ME Hasselmo, DJ Cai - Elife, 2020 - elifesciences.org
While memories are often thought of as flashbacks to a previous experience, they do not
simply conserve veridical representations of the past but must continually integrate new …

Long-duration hippocampal sharp wave ripples improve memory

A Fernández-Ruiz, A Oliva, E Fermino de Oliveira… - Science, 2019 - science.org
Hippocampal sharp wave ripples (SPW-Rs) have been hypothesized as a mechanism for
memory consolidation and action planning. The duration of ripples shows a skewed …

Associative and predictive hippocampal codes support memory-guided behaviors

C Liu, R Todorova, W Tang, A Oliva, A Fernandez-Ruiz - Science, 2023 - science.org
Episodic memory involves learning and recalling associations between items and their
spatiotemporal context. Those memories can be further used to generate internal models of …

Constant sub-second cycling between representations of possible futures in the hippocampus

K Kay, JE Chung, M Sosa, JS Schor, MP Karlsson… - Cell, 2020 - cell.com
Cognitive faculties such as imagination, planning, and decision-making entail the ability to
represent hypothetical experience. Crucially, animal behavior in natural settings implies that …

Time cells in the human hippocampus and entorhinal cortex support episodic memory

G Umbach, P Kantak, J Jacobs… - Proceedings of the …, 2020 - National Acad Sciences
The organization of temporal information is critical for the encoding and retrieval of episodic
memories. In the rodent hippocampus and entorhinal cortex, evidence accumulated over the …

How development sculpts hippocampal circuits and function

R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …

Alternating sequences of future and past behavior encoded within hippocampal theta oscillations

M Wang, DJ Foster, BE Pfeiffer - Science, 2020 - science.org
Neural networks display the ability to transform forward-ordered activity patterns into reverse-
ordered, retrospective sequences. The mechanisms underlying this transformation remain …

The generative grammar of the brain: a critique of internally generated representations

G Dragoi - Nature Reviews Neuroscience, 2024 - nature.com
The past decade of progress in neurobiology has uncovered important organizational
principles for network preconfiguration and neuronal selection that suggest a generative …

Multiple time-scales of decision-making in the hippocampus and prefrontal cortex

W Tang, JD Shin, SP Jadhav - Elife, 2021 - elifesciences.org
The prefrontal cortex and hippocampus are crucial for memory-guided decision-making.
Neural activity in the hippocampus exhibits place-cell sequences at multiple timescales …