Can cysteine protease cross-class inhibitors achieve selectivity?
L Cianni, CW Feldmann, E Gilberg… - Journal of medicinal …, 2019 - ACS Publications
Cysteine proteases are important targets for the discovery of novel therapeutics for many
human diseases. From parasitic diseases to cancer, cysteine proteases follow a common …
human diseases. From parasitic diseases to cancer, cysteine proteases follow a common …
Trypanosoma cruzi killing and immune response boosting by novel phenoxyhydrazine-thiazole against Chagas disease
AC Cristovão-Silva, MCA Brelaz-de-Castro… - Experimental …, 2024 - Elsevier
Trypanosoma cruzi (T. cruzi) causes Chagas, which is a neglected tropical disease (NTD).
WHO estimates that 6 to 7 million people are infected worldwide. Current treatment is done …
WHO estimates that 6 to 7 million people are infected worldwide. Current treatment is done …