miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers

AS Doghish, A Ismail, HA El-Mahdy, SY Elkhawaga… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …

RBP–RNA interactions in the control of autoimmunity and autoinflammation

J Liu, X Cao - Cell research, 2023 - nature.com
Autoimmunity and autoinflammation arise from aberrant immunological and inflammatory
responses toward self-components, contributing to various autoimmune diseases and …

[HTML][HTML] Gut microbiota in pre-clinical rheumatoid arthritis: From pathogenesis to preventing progression

L Lin, K Zhang, Q Xiong, J Zhang, B Cai, Z Huang… - Journal of …, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive
polyarthritis that leads to cartilage and bone damage. Pre-clinical RA is a prolonged state …

miRNAs as biomarkers and possible therapeutic strategies in rheumatoid arthritis

T Kmiołek, A Paradowska-Gorycka - Cells, 2022 - mdpi.com
Within the past years, more and more attention has been devoted to the epigenetic
dysregulation that provides an additional window for understanding the possible …

Comprehensive overview of microRNA function in rheumatoid arthritis

X Peng, Q Wang, W Li, G Ge, J Peng, Y Xu, H Yang… - Bone Research, 2023 - nature.com
MicroRNAs (miRNAs), a class of endogenous single-stranded short noncoding RNAs, have
emerged as vital epigenetic regulators of both pathological and physiological processes in …

[HTML][HTML] The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis

J Yang, Z Li, L Wang, X Yun, Y Zeng, JPL Ng… - Pharmacological …, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder which is associated
with the dysregulation of autoimmune response. In recent years, early diagnosis, aggressive …

Functional interactions between lncRNAs/circRNAs and miRNAs: insights into rheumatoid arthritis

JJ Han, XQ Wang, XA Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases that affect
synovitis, bone, cartilage, and joint. RA leads to bone and cartilage damage and extra …

Role of miRNAs in rheumatoid arthritis therapy

Y Zhang, M Yang, H Xie, F Hong, S Yang - Cells, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by
autoimmunity, synovial inflammation and joint destruction. Pannus formation in the synovial …

Immunosenescence of T cells: a key player in rheumatoid arthritis

Y Gao, W Cai, Y Zhou, Y Li, J Cheng, F Wei - Inflammation Research, 2022 - Springer
Introduction The incidence of rheumatoid arthritis (RA) and its complications are expected to
increase with age. Remarkably, RA patients were identified features of accelerated aging …

S1P increases VEGF production in osteoblasts and facilitates endothelial progenitor cell angiogenesis by inhibiting miR-16-5p expression via the c-Src/FAK signaling …

CC Huang, TT Tseng, SC Liu, YY Lin, YY Law, SL Hu… - Cells, 2021 - mdpi.com
Angiogenesis is a critical process in the formation of new capillaries and a key participant in
rheumatoid arthritis (RA) pathogenesis. Vascular endothelial growth factor (VEGF) …