Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and
common cause of non-traumatic neurological disability in young adults. The likelihood for an …

Multiple sclerosis (MS) is a common, complex neurological disease. The precise aetiology of
MS is not yet known, although epidemiological data indicate that both genetic and …

Association studies have greatly refined the understanding of how variation within the
human leukocyte antigen (HLA) genes influences risk of multiple sclerosis. However, the …

The complex network of specialized cells and molecules in the immune system has evolved
to defend against pathogens, but inadvertent immune system attacks on" self" result in …

Multiple sclerosis (MS) is a chronic, progressive disorder of the central nervous system
(CNS) that affects more than two million people worldwide. Several animal models resemble …

Zinc is an essential trace element for living organisms and their biological processes. Zinc
plays a key role in more than 300 enzymes and it is involved in cell communication …

Genome-wide association studies have revolutionised the genetic analysis of multiple
sclerosis. Through international collaborative efforts involving tens of thousands of cases …

Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …

The HLA region encodes several molecules that play key roles in the immune system.
Strong association between the HLA region and autoimmune disease (AID) has been …

The major histocompatibility complex (MHC) is one of the most extensively studied regions
in the human genome because of the association of variants at this locus with autoimmune …