How I treat juvenile myelomonocytic leukemia

F Locatelli, CM Niemeyer - Blood, The Journal of the American …, 2015 - ashpublications.org
Juvenile myelomonocytic leukemia (JMML) is a unique, aggressive hematopoietic disorder
of infancy/early childhood caused by excessive proliferation of cells of monocytic and …

Recent advances in the pathogenesis and treatment of juvenile myelomonocytic leukaemia

ML Loh - British journal of haematology, 2011 - Wiley Online Library
Myeloid neoplasms derive from the pathological clonal expansion of an abnormal stem cell
and span a diverse spectrum of phenotypes including acute myeloid leukaemia (AML) …

[HTML][HTML] An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of …

TI Mughal, NCP Cross, E Padron, RV Tiu… - …, 2015 - ncbi.nlm.nih.gov
In the 2008 WHO classification, chronic myeloid malignancies that share both
myelodysplastic and myeloproliferative features define the myelodysplastic …

Donor lymphocyte infusion following allogeneic hematopoietic stem cell transplantation

C Roddie, KS Peggs - Expert opinion on biological therapy, 2011 - Taylor & Francis
Introduction: Allogeneic hematopoietic stem cell transplantation (SCT) is the treatment of
choice for many malignant hematological disorders. Following recent improvements in non …

[HTML][HTML] Juvenile myelomonocytic leukemia-A comprehensive review and recent advances in management

AK Gupta, JP Meena, A Chopra… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Juvenile myelomonocytic leukemia (JMML) is a rare pediatric myelodysplastic/
myeloproliferative neoplasm overlap disease. JMML is associated with mutations in the RAS …

Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia: molecular classification and treatment options

CM Niemeyer, CP Kratz - British journal of haematology, 2008 - Wiley Online Library
Myelodysplastic syndromes (MDS) and the mixed myelodysplastic/myeloproliferative
disorder juvenile myelomonocytic leukaemia (JMML) are rare haematopoietic stem cell …

Juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia

PD Emanuel - Leukemia, 2008 - nature.com
In 1982, chronic myelomonocytic leukemia (CMML) was first classified in the category of
myelodysplastic syndromes (MDSs), but it always seemed somewhat out of place compared …

Clinical management of myelodysplastic syndromes: update of SIE, SIES, GITMO practice guidelines

V Santini, PE Alessandrino, E Angelucci, G Barosi… - Leukemia research, 2010 - Elsevier
Since 2002, date of publication of the previous Italian Society of Haematology (SIE) practice
guidelines for management of myelodysplastic syndromes (MDS), novel disease-modifying …

[HTML][HTML] DNA-hypomethylating agents as epigenetic therapy before and after allogeneic hematopoietic stem cell transplantation in myelodysplastic syndromes and …

C Flotho, S Sommer, M Lübbert - Seminars in cancer biology, 2018 - Elsevier
Myelodysplastic syndrome (MDS) is a clonal bone marrow disorder, typically of older adults,
which is characterized by ineffective hematopoiesis, peripheral blood cytopenias and risk of …

Juvenile myelomonocytic leukemia in the molecular era: a clinician's guide to diagnosis, risk stratification, and treatment

A Wintering, CC Dvorak, E Stieglitz, ML Loh - Blood advances, 2021 - ashpublications.org
Juvenile myelomonocytic leukemia is an overlapping myeloproliferative and
myelodysplastic disorder of early childhood. It is associated with a spectrum of diverse …