Unmasking the deceptive nature of cancer stem cells: The role of cd133 in revealing their secrets
J Pospieszna, H Dams-Kozlowska, W Udomsak… - International Journal of …, 2023 - mdpi.com
Cancer remains a leading cause of death globally, and its complexity poses a significant
challenge to effective treatment. Cancer stem cells and their markers have become key …
challenge to effective treatment. Cancer stem cells and their markers have become key …
Tumor microenvironment-induced tumor cell plasticity: relationship with hypoxic stress and impact on tumor resistance
The role of tumor interaction with stromal components during carcinogenesis is crucial for
the design of efficient cancer treatment approaches. It is widely admitted that tumor hypoxic …
the design of efficient cancer treatment approaches. It is widely admitted that tumor hypoxic …
GART Functions as a Novel Methyltransferase in the RUVBL1/β‐Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer
C Tang, M Ke, X Yu, S Sun, X Luo, X Liu… - Advanced …, 2023 - Wiley Online Library
Tumor stemness is associated with the recurrence and incurability of colorectal cancer
(CRC), which lacks effective therapeutic targets and drugs. Glycinamide ribonucleotide …
(CRC), which lacks effective therapeutic targets and drugs. Glycinamide ribonucleotide …
The role of alpha-fetoprotein in the tumor microenvironment of hepatocellular carcinoma
Y Lu, B Lin, M Li - Frontiers in Oncology, 2024 - frontiersin.org
Hepatocellular carcinoma (HCC) is a prevalent malignant cancer worldwide, characterized
by high morbidity and mortality rates. Alpha-fetoprotein (AFP) is a glycoprotein synthesized …
by high morbidity and mortality rates. Alpha-fetoprotein (AFP) is a glycoprotein synthesized …
Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular …
Q Wu, X Li, M Long, X Xie, Q Liu - Scientific Reports, 2023 - nature.com
Histone lysine lactylation (Kla) plays a vital role in the tumorigenesis of hepatocellular
carcinoma (HCC). Hence, we focused on Kla-specific genes to select novel therapeutic …
carcinoma (HCC). Hence, we focused on Kla-specific genes to select novel therapeutic …
Rab11-FIP4 interacts with ARF5 to promote cancer stemness in hepatocellular carcinoma
F Song, Q Zhang, X Lu, T Xu, Q Hu, X Hu… - Journal of physiology …, 2023 - Springer
Recent studies suggest that Rab11-family interacting proteins (Rab11-FIPs) play an
important role in tumorigenesis and progression. Among the Rab11-FIPs, Rab11-FIP4 has …
important role in tumorigenesis and progression. Among the Rab11-FIPs, Rab11-FIP4 has …
Clonorchis sinensis infection amplifies hepatocellular carcinoma stemness, predicting unfavorable prognosis
Q Lin, Z Tang, Y Qin, X Deng, C Wei, F Liu… - PLOS Neglected …, 2024 - journals.plos.org
Background Extensive evidence links Clonorchis sinensis (C. sinensis) to
cholangiocarcinoma; however, its association with hepatocellular carcinoma (HCC) is less …
cholangiocarcinoma; however, its association with hepatocellular carcinoma (HCC) is less …
[HTML][HTML] RUNX2 prompts triple negative breast cancer drug resistance through TGF-β pathway regulating breast cancer stem cells
F Lv, W Si, X Xu, X He, Y Wang, Y Li, F Li - Neoplasia, 2024 - Elsevier
Triple-negative breast cancer (TNBC) stands out as the most aggressive subtype within the
spectrum of breast cancer. The current clinical guidelines propose treatment strategies …
spectrum of breast cancer. The current clinical guidelines propose treatment strategies …
Reappraisal of the Roles of the Sonic Hedgehog Signaling Pathway in Hepatocellular Carcinoma
KS Jeng, CF Chang, YM Tsang, IS Sheen, CJ Jeng - Cancers, 2024 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) remains one of the leading causes of
cancer mortality. Treatment of HCC remains challenging, especially for those with advanced …
cancer mortality. Treatment of HCC remains challenging, especially for those with advanced …
[HTML][HTML] Combating drug resistance in hepatocellular carcinoma: No awareness today, no action tomorrow
F Jing, X Li, H Jiang, J Sun, Q Guo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Hepatocellular carcinoma (HCC), the sixth most common cancer worldwide, is associated
with a high degree of malignancy and poor prognosis. Patients with early HCC may benefit …
with a high degree of malignancy and poor prognosis. Patients with early HCC may benefit …