Pancreatitis is a fibro-inflammatory disorder of the pancreas that can occur acutely or
chronically as a result of the activation of digestive enzymes that damage pancreatic cells …

As a member of the IL-17 cytokine family, IL-25 (also called IL-17E) induces and sustains
type 2 immunity. IL-25, which is mainly produced by intestinal epithelial cells, has been …

Allergic asthma is a frequently encountered and well described asthma phenotype.
However, its precise mechanisms are less known. The tools for targeted selection of patients …

Observational studies have shown close associations between COVID-19 risk and
cytokines, especially interleukins (ILs) and interferons (IFNs). However, the causal …

Stroke is the leading cause of death and the main cause of disability in surviving patients.
The detrimental interaction between immune cells, glial cells, and matrix components in …

The IL-4/IL-13 axis is involved in the pathogenesis of allergic rhinitis (AR). In this study, we
investigated the serum cytokines levels of IL-4, IL-5, IL-6, and IL-13 in AR patients, and the …

Eosinophils are bi-lobed, multi-functional innate immune cells with diverse cell surface
receptors that regulate local immune and inflammatory responses. Several inflammatory and …

Autoinflammatory diseases are a group of clinical syndromes characterized by constitutive
overactivation of innate immune pathways. This results in increased production of or …

Reports indicate that accumulated macrophages in the pancreas are responsible for
promoting the pathogenesis of chronic pancreatitis (CP). Recently, macrophage-secreted …

Abstract Eosinophils comprise approximately 1–4% of total blood leukocytes that reside in
the intestine, bone marrow, mammary gland, and adipose tissues to maintain innate …