Interleukin IL-5 alleviates sepsis-induced acute lung injury by regulating the immune response in rats

B Wei, Y Chen, W Zhou, X Li, L Shi, S Liao - Bioengineered, 2021 - Taylor & Francis
To study the effect of IL-5 on the immune response and lung injury in rats with sepsis. We
constructed a rat model of sepsis by cecal ligation and puncture (CLP). The rats were …

Psychiatric manifestations of COVID-19: a literature review

A Khatun, T Tamilanban, V Chitra - CNS & Neurological …, 2023 - ingentaconnect.com
Background: COVID-19 (coronavirus disease of 2019) occurs due to the highly contagious
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It uses angiotensin …

[HTML][HTML] Insight into IL-5 as a Potential Target for the Treatment of Allergic Diseases

K Antosz, J Batko, M Błażejewska, A Gawor, J Sleziak… - Biomedicines, 2024 - mdpi.com
Interleukin-5 functions as a B-cell differentiation factor, but more importantly, in the context of
this review, it plays a variety of roles in eosinophil biology, including eosinophil …

Chronic inflammation promotes epithelial-mesenchymal transition-mediated malignant phenotypes and lung injury in experimentally-induced pancreatitis

HK Kandikattu, M Manohar, SU Venkateshaiah… - Life sciences, 2021 - Elsevier
Patients with chronic pancreatitis have an increased risk of pancreatic malignancy, but the
mechanisms underlying this relationship are poorly understood. We developed a mouse …

Shegan-Mahuang Decoction ameliorates cold-induced asthma via regulating the proliferation and apoptosis of airway smooth muscle cells through TAS2R10: An in …

Q Li, X Shan, Y Yuan, W Ye, X Fang - Journal of Ethnopharmacology, 2024 - Elsevier
Abstract Ethnopharmacological relevance Shegan-Mahuang Decoction (SMD) is a classical
formula that has been used to effectively treat cold-induced asthma (CA) for 1800 years …

Allergens induce upregulated IL-18 and IL-18Rα expression in blood Th2 and Th17 cells of patients with allergic asthma

J Wang, M Zhan, Y Zhai, S Wang, F Gu… - Clinical and …, 2024 - academic.oup.com
Allergic asthma (AA) is closely associated with the polarization of T helper (Th) 2 and Th17
cells. Interleukin (IL)-18 acts as an inducer of Th2 and Th17 cell responses. However …

Administration of a bacterial lysate to the airway compartment is sufficient to inhibit allergen-induced lung eosinophilia in germ-free mice

AN Michael, O Pivniouk, PC Ezeh… - Journal of Leukocyte …, 2024 - academic.oup.com
The nexus between eosinophils and microbes is attracting increasing attention. We
previously showed that airway administration of sterile microbial products contained in dust …

[HTML][HTML] Safety and efficacy of complementary medicines for eosinophilic gastrointestinal disorders in adults: a systematic review and exploration of candidate …

N Hannan, J Schloss, MJ Leach - Advances in Integrative Medicine, 2023 - Elsevier
Eosinophilic gastrointestinal disorders (EGIDs) are a group of Th2-mediated antigen-driven
conditions. The limitations of conventional management options (ie invasive monitoring …

IL-5 enhances the resistance of Actinobacillus pleuropneumoniae infection in mice through maintaining appropriate levels of lung M2, PMN-II and highly effective …

P Chen, C Bao, R Zhu, J Wang, J Zhu, Z Li, F Li… - Veterinary …, 2022 - Elsevier
Abstract Interleukin 5 (IL-5) regulates the maturation, activation, proliferation and function of
immune cells, and plays an important role in the inflammatory response induced by an …

Peripheral Eosinophil Count Is Associated With the Prognosis of Patients With Type B Aortic Dissection Undergoing Endovascular Aortic Repair: A Retrospective …

K Zhao, H Zhu, J Ma, Z Zhao, L Zhang… - Journal of the …, 2022 - Am Heart Assoc
Background Eosinophil count (EOS) has been proposed to provide prognostic information in
multiple cardiovascular disorders. However, few researchers have investigated the …