Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

CD30, a member of the tumor necrosis factor receptor superfamily, plays roles in pro-
survival signal induction and cell proliferation in peripheral T-cell lymphoma (PTCL) and …

Epigenomes enable the rectification of disordered cancer gene expression, thereby
providing new targets for pharmacological interventions. The clinical utility of targeting …

Human T cell leukemia virus type 1 (HTLV-1) mainly infects CD4+ T cells and induces
chronic, persistent infection in infected individuals, with some developing adult T cell …

Viral infection is an indisputable causal factor for nearly 17% of all human cancers.
However, the diversity and complexity of oncogenic mechanisms raises new questions as to …

Human T-cell leukemia virus type I (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL)
in 5% of infected people with a decades-long latency. Charles RM Bangham reviews the …

Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature CD4+ T cells induced by
human T-cell leukemia virus type I (HTLV-1). HTLV-1 maintains life-long infection in the …

Adult T cell leukemia/lymphoma (ATL) is an aggressive malignancy secondary to chronic
infection with human T cell leukemia virus type 1 (HTLV-1). The viral oncoprotein Tax …

Human T-cell leukemia virus type 1 (HTLV-1) is a replication-competent human retrovirus
associated with two distinct types of diseases: a malignancy of mature CD4+ T cells called …

The Human T-cell Leukemia virus type 1 (HTLV-1) causes an array of pathologies, the most
aggressive of which is adult T-cell leukemia (ATL), a fatal blood malignancy with dismal …