Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma

KMM Espíndola, RG Ferreira, LEM Narvaez… - Frontiers in …, 2019 - frontiersin.org
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in
foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid …

Nutritional constituent and health benefits of chickpea (Cicer arietinum L.): A review

J Wang, Y Li, A Li, RH Liu, X Gao, D Li, X Kou… - Food Research …, 2021 - Elsevier
Abstract Chickpea (Cicer arietinum L.), an annual plant of the Fabaceae family, is mainly
grown in temperate and semiarid regions. Its biological activity and beneficial contribution to …

Biochanin A: A novel bioactive multifunctional compound from nature

A Sarfraz, M Javeed, MA Shah, G Hussain… - Science of the Total …, 2020 - Elsevier
Natural products (NPs) will continue to serve humans as matchless source of novel drug
leads and an inspiration for the synthesis of non-natural drugs. As our scientific …

Flavonoids as a natural enhancer of neuroplasticity—An overview of the mechanism of neurorestorative action

N Cichon, J Saluk-Bijak, L Gorniak, L Przyslo, M Bijak - Antioxidants, 2020 - mdpi.com
Neuroplasticity is a complex physiological process occurring in the brain for its entire life.
However, it is of particular importance in the case of central nervous system (CNS) …

Network pharmacology and molecular docking technology-based predictive study of the active ingredients and potential targets of rhubarb for the treatment of diabetic …

S Fu, Y Zhou, C Hu, Z Xu, J Hou - BMC complementary medicine and …, 2022 - Springer
Diabetic nephropathy (DN) is one of the most serious complications of diabetes and the
main cause of end-stage renal failure. Rhubarb is a widely used traditional Chinese herb …

Perspectives regarding the role of biochanin A in humans

C Yu, P Zhang, L Lou, Y Wang - Frontiers in pharmacology, 2019 - frontiersin.org
Biochanin A (BCA) is an isoflavone mainly found in red clover with poor solubility and oral
absorption that is known to have various effects, including anti-inflammatory, estrogen-like …

System biology-based investigation of Silymarin to trace hepatoprotective effect

PSR Dwivedi, VS Patil, P Khanal, VV Bhandare… - Computers in biology …, 2022 - Elsevier
Silymarin is used as a hepatoprotective agent since ancient times which could be via its
potent anti-oxidant effect. However, the mode of silymarin for the hepatoprotective effect has …

Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti‐inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway

P Chen, J Zhou, A Ruan, L Zeng, J Liu… - Journal of Cellular and …, 2022 - Wiley Online Library
Cinnamon is a wildly used traditional Chinese herbal medicine for osteoarthritis (OA)
treatment, but the underlying mechanism remains ambiguous. The purpose of this study is to …

Exploring Active Ingredients, Beneficial Effects, and Potential Mechanism of Allium tenuissimum L. Flower for Treating T2DM Mice Based on Network Pharmacology …

SS Zhang, YF Hou, SJ Liu, S Guo, CT Ho, NS Bai - Nutrients, 2022 - mdpi.com
Forty compounds were isolated and characterized from A. tenuissimum flower. Among them,
twelve flavonoids showed higher α− glucosidase inhibition activities in vitro than acarbose …

Involvement of Xeroderma Pigmentosum Complementation Group G (XPG) in epigenetic regulation of T-Helper (TH) cell differentiation during breast cancer

R Pal, S Rakshit, G Shanmugam, N Paul… - Immunobiology, 2022 - Elsevier
TNFα and IFN-γ secreted by CD4+ T-Helper (TH) cells have antitumor activity followed by
polarisation of TH 1 phenotype in response to IL-12 secreted by dendritic cells, inducing …