Molecular dynamics simulations of G-DNA and perspectives on the simulation of nucleic acid structures
J Šponer, X Cang, TE Cheatham III - Methods, 2012 - Elsevier
The article reviews the application of biomolecular simulation methods to understand the
structure, dynamics and interactions of nucleic acids with a focus on explicit solvent …
structure, dynamics and interactions of nucleic acids with a focus on explicit solvent …
Controllable cy3-MTC-dye aggregates and its applications served as a chemosensor
L Wang, J Xiang, H Sun, Q Yang, L Yu, Q Li, A Guan… - Dyes and …, 2015 - Elsevier
The cyanine dyes are among the oldest classes of synthetic compounds but continue to find
applications in a variety of fields. Compared to other organic molecules, diverse and …
applications in a variety of fields. Compared to other organic molecules, diverse and …
Quantification of the Na+/K+ ratio based on the different response of a newly identified G-quadruplex to Na+ and K+
H Sun, J Xiang, W Gai, Y Liu, A Guan, Q Yang… - Chemical …, 2013 - pubs.rsc.org
A G-quadruplex is identified which can exhibit two different motifs, respectively,
corresponding to Na+ and K+. The relative amount of each motif is related to the Na+/K+ …
corresponding to Na+ and K+. The relative amount of each motif is related to the Na+/K+ …
[HTML][HTML] Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations
Several ligands can bind to the non-canonical G-quadruplex DNA structures thereby
stabilizing them. These molecules can act as effective anticancer agents by stabilizing the …
stabilizing them. These molecules can act as effective anticancer agents by stabilizing the …
Probing the interaction of distamycin A with S100β: the “unexpected” ability of S100β to bind to DNA‐binding ligands
L Cerofolini, J Amato, V Borsi, B Pagano… - Journal of Molecular …, 2015 - Wiley Online Library
DNA‐minor‐groove‐binding ligands are potent antineoplastic molecules. The antibiotic
distamycin A is the prototype of one class of these DNA‐interfering molecules that have …
distamycin A is the prototype of one class of these DNA‐interfering molecules that have …
[HTML][HTML] Конформационная динамика нуклеиновых кислот при взаимодействии с лигандами
АВ Головин - 2014 - dissercat.com
Сложная трёхмерная организация биологических макромолекул определяет их
биологическую функцию. Благодаря успехам современной структурной химии, мы …
биологическую функцию. Благодаря успехам современной структурной химии, мы …