Intelligent DNA-based Hydrogels: An Outstanding Programable and Biocompatible Material for Food Applications

G Li, H Huang, L Zou, X Zhang, X Lin, M Javed… - Trends in Food Science …, 2024 - Elsevier
Background Biocompatible smart materials have ushered in revolutionary applications,
conferring significant benefits upon humanity. Among these materials, DNA hydrogels stand …

Engineering DNA-based cytoskeletons for synthetic cells

K Jahnke, K Göpfrich - Interface Focus, 2023 - royalsocietypublishing.org
The development and bottom-up assembly of synthetic cells with a functional cytoskeleton
sets a major milestone to understand cell mechanics and to develop man-made machines …

DNA origami signaling units transduce chemical and mechanical signals in synthetic cells

K Jahnke, M Illig, M Scheffold, MP Tran… - Advanced Functional …, 2024 - Wiley Online Library
Transmembrane proteins transmit chemical signals as well as mechanical cues. The latter is
often achieved by coupling to the cytoskeleton. The incorporation of fully engineerable …

Facile and programmable capillary-induced assembly of prototissues via hanging drop arrays

C Qi, X Ma, J Zhong, J Fang, Y Huang, X Deng… - ACS …, 2023 - ACS Publications
An important goal for bottom-up synthetic biology is to construct tissue-like structures from
artificial cells. The key is the ability to control the assembly of the individual artificial cells …

[HTML][HTML] Artificial cells for in vivo biomedical applications through red blood cell biomimicry

J Waeterschoot, W Gosselé, Š Lemež… - Nature …, 2024 - nature.com
Recent research in artificial cell production holds promise for the development of delivery
agents with therapeutic effects akin to real cells. To succeed in these applications, these …

Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks

V Maffeis, L Heuberger, A Nikoletić… - Advanced …, 2024 - Wiley Online Library
The exponential growth of research on artificial cells and organelles underscores their
potential as tools to advance the understanding of fundamental biological processes. The …

[HTML][HTML] Designer peptide–DNA cytoskeletons regulate the function of synthetic cells

ML Daly, K Nishi, SJ Klawa, KY Hinton, Y Gao… - Nature Chemistry, 2024 - nature.com
The bottom-up engineering of artificial cells requires a reconfigurable cytoskeleton that can
organize at distinct locations and dynamically modulate its structural and mechanical …

Chemotactic interactions drive migration of membraneless active droplets

M Dindo, A Bevilacqua, G Soligo… - Journal of the …, 2024 - ACS Publications
In nature, chemotactic interactions are ubiquitous and play a critical role in driving the
collective behavior of living organisms. Reproducing these interactions in vitro is still a …

Functional metal-phenolic cortical cytoskeleton for artificial cells

ZH Luo, C Chen, QH Zhao, NN Deng - Science Advances, 2024 - science.org
Cortex-like cytoskeleton, a thin layer of cross-linked cytoplasmic proteins underlying the cell
membrane, plays an essential role in modulating membrane behavior and cell surface …

DNA-empowered synthetic cells as minimalistic life forms

A Samanta, L Baranda Pellejero, M Masukawa… - Nature Reviews …, 2024 - nature.com
Cells, the fundamental units of life, orchestrate intricate functions—motility, adaptation,
replication, communication, and self-organization within tissues. Originating from …