Reading, writing and erasing mRNA methylation
S Zaccara, RJ Ries, SR Jaffrey - Nature reviews Molecular cell biology, 2019 - nature.com
RNA methylation to form N 6-methyladenosine (m6A) in mRNA accounts for the most
abundant mRNA internal modification and has emerged as a widespread regulatory …
abundant mRNA internal modification and has emerged as a widespread regulatory …
Insights into N6-methyladenosine and programmed cell death in cancer
L Liu, H Li, D Hu, Y Wang, W Shao, J Zhong, S Yang… - Molecular cancer, 2022 - Springer
Abstract N6-methyladenosine (m6A) methylation, the most common form of internal RNA
modification in eukaryotes, has gained increasing attention and become a hot research topic …
modification in eukaryotes, has gained increasing attention and become a hot research topic …
METTL3 promotes chemoresistance in small cell lung cancer by inducing mitophagy
Y Sun, W Shen, S Hu, Q Lyu, Q Wang, T Wei… - Journal of Experimental …, 2023 - Springer
Background Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer.
Although most patients are initially sensitive to first-line combination chemotherapy with …
Although most patients are initially sensitive to first-line combination chemotherapy with …
Structural basis for cooperative function of Mettl3 and Mettl14 methyltransferases
Summary N 6-methyladenosine (m 6 A) is a prevalent, reversible chemical modification of
functional RNAs and is important for central events in biology. The core m 6 A writers are …
functional RNAs and is important for central events in biology. The core m 6 A writers are …
Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex
Chemical modifications of RNA have essential roles in a vast range of cellular processes,,. N
6-methyladenosine (m6A) is an abundant internal modification in messenger RNA and long …
6-methyladenosine (m6A) is an abundant internal modification in messenger RNA and long …
Means, mechanisms and consequences of adenine methylation in DNA
K Boulias, EL Greer - Nature Reviews Genetics, 2022 - nature.com
Abstract N 6-methyl-2′-deoxyadenosine (6mA or m6dA) has been reported in the DNA of
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase
INTRODUCTION N 6-methyladenosine (m6A), an abundant modification in eukaryotic
mRNAs and long-noncoding RNAs, has been recognized as a major epitranscriptome mark …
mRNAs and long-noncoding RNAs, has been recognized as a major epitranscriptome mark …
Structural insights into the molecular mechanism of the m6A writer complex
P Śledź, M Jinek - elife, 2016 - elifesciences.org
Methylation of adenosines at the N6 position (m6A) is a dynamic and abundant
epitranscriptomic mark that regulates critical aspects of eukaryotic RNA metabolism in …
epitranscriptomic mark that regulates critical aspects of eukaryotic RNA metabolism in …
Dynamics of DNA methylation and its functions in plant growth and development
S Kumar, T Mohapatra - Frontiers in Plant Science, 2021 - frontiersin.org
Epigenetic modifications in DNA bases and histone proteins play important roles in the
regulation of gene expression and genome stability. Chemical modification of DNA base …
regulation of gene expression and genome stability. Chemical modification of DNA base …
Epigenetics of modified DNA bases: 5-methylcytosine and beyond
S Kumar, V Chinnusamy, T Mohapatra - Frontiers in genetics, 2018 - frontiersin.org
Modification of DNA bases plays vital roles in the epigenetic control of gene expression in
both animals and plants. Though much attention is given to the conventional epigenetic …
both animals and plants. Though much attention is given to the conventional epigenetic …