EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Endocrine disrupting chemicals: Impacts on human fertility and fecundity during the peri-conception period

MP Green, AJ Harvey, BJ Finger, GA Tarulli - Environmental research, 2021 - Elsevier
It is becoming increasingly difficult to avoid exposure to man-made endocrine disrupting
chemicals (EDCs) and environmental toxicants. This escalating yet constant exposure is …

Environmental pollutants, a possible etiology for premature ovarian insufficiency: a narrative review of animal and human data

P Vabre, N Gatimel, J Moreau, V Gayrard… - Environmental …, 2017 - Springer
Background Because only 25% of cases of premature ovarian insufficiency (POI) have a
known etiology, the aim of this review was to summarize the associations and mechanisms …

Multi-and transgenerational outcomes of an exposure to a mixture of endocrine-disrupting chemicals (EDCs) on puberty and maternal behavior in the female rat

D López-Rodríguez, CF Aylwin, V Delli… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: The effects of endocrine-disrupting chemicals (EDCs) on fertility and
reproductive development represent a rising concern in modern societies. Although the …

Prenatal exposure to di (2-ethylhexyl) phthalate causes long-term transgenerational effects on female reproduction in mice

E Brehm, S Rattan, L Gao, JA Flaws - Endocrinology, 2018 - academic.oup.com
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer in many consumer products.
Although DEHP is a known endocrine disruptor, little is known about the effects of DEHP …

Effects of phthalate mixtures on ovarian folliculogenesis and steroidogenesis

EJ Fletcher, R Santacruz-Márquez, VE Mourikes… - Toxics, 2022 - mdpi.com
The female reproductive system is dependent upon the health of the ovaries. The ovaries
are responsible for regulating reproduction and endocrine function. Throughout a female's …

[HTML][HTML] Di (2-ethylhexyl) phthalate-induced reproductive toxicity involved in DNA damage-dependent oocyte apoptosis and oxidative stress in Caenorhabditis …

J Yin, R Liu, Z Jian, D Yang, Y Pu, L Yin… - … and environmental safety, 2018 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer with a high
environmental exposure level. As a persistent organic pollutant, DEHP causes reproductive …

Prenatal exposure to DEHP induces premature reproductive senescence in male mice

R Barakat, PCP Lin, S Rattan, E Brehm… - Toxicological …, 2017 - academic.oup.com
Di-(2-ethylhexyl) phthalate (DEHP) is the most commonly used phthalate, and it is an
endocrine-disrupting chemical. This study tested a hypothesis that prenatal exposure to …

Prenatal exposure to DEHP induces neuronal degeneration and neurobehavioral abnormalities in adult male mice

R Barakat, PC Lin, CJ Park… - Toxicological …, 2018 - academic.oup.com
Phthalates are a family of synthetic chemicals that are used in producing a variety of
consumer products. Di-(2-ethylhexyl) phthalate (DEHP) is an widely used phthalate and …

DEHP and DINP induce tissue-and gender-specific disturbances in fatty acid and lipidomic profiles in neonatal mice: a comparative study

Y Huang, F Sun, H Tan, Y Deng, Z Sun… - … science & technology, 2019 - ACS Publications
Di-isononyl phthalate (DINP) is considered one of the main industrial alternatives to di (2-
ethylhexyl) phthalate (DEHP), a well-known chemical with various toxic effects including the …