Longitudinal changes of white matter hyperintensities in sporadic small vessel disease: a systematic review and meta-analysis

ACC Jochems, C Arteaga, F Chappell, T Ritakari… - Neurology, 2022 - AAN Enterprises
Background and Objectives White matter hyperintensities (WMHs) are frequent imaging
features of small vessel disease (SVD) and related to poor clinical outcomes. WMH …

Visualizing Cerebral Small Vessel Degeneration During Aging and Diseases Using Magnetic Resonance Imaging

P Huang, K Chen, C Liu, Z Zhen… - Journal of Magnetic …, 2023 - Wiley Online Library
Cerebral small vessel disease is a major contributor to brain disorders in older adults. It is
associated with a much higher risk of stroke and dementia. Due to a lack of clinical and fluid …

Pro‐Hemorrhagic Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Associated with NOTCH3 p.R75P Mutation with …

H Ishiyama, H Kim, S Saito, S Takeda… - Annals of …, 2024 - Wiley Online Library
Objectives Intracerebral hemorrhage (ICH) and cerebral microbleeds (CMB) in cerebral
autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy are …

The frequency and characteristics of multiple sclerosis misdiagnosis in Latin America: A referral center study in Buenos Aires, Argentina

MI Gaitán, M Sanchez, MF Farez… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Objective: Most contemporary data concerning the frequency and causes of multiple
sclerosis (MS) misdiagnosis are from North America and Europe with different healthcare …

How often does white matter hyperintensity volume regress in cerebral small vessel disease?

RB Brown, DJ Tozer, M Egle… - … Journal of Stroke, 2023 - journals.sagepub.com
Background and objectives: It has been suggested that white matter hyperintensity lesions
(WMHs), which typically progress over time, can also regress, and that this might be …

Regional White Matter Hyperintensities and Alzheimer's Disease Biomarkers Among Older Adults with Normal Cognition and Mild Cognitive Impairment

P Newton, J Tchounguen, C Pettigrew… - Journal of …, 2023 - content.iospress.com
Background: Alzheimer's disease (AD) frequently co-occurs with other brain pathologies.
Recent studies suggest there may be a mechanistic link between AD and small vessel …

Amyloid deposition and small vessel disease are associated with cognitive function in older adults with type 2 diabetes

OH Lesman-Segev, S Golan Shekhtman… - Scientific Reports, 2024 - nature.com
Diabetes is associated with cognitive decline, but the underlying mechanisms are complex
and their relationship with Alzheimer's Disease biomarkers is not fully understood. We …

Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia

M Sargurupremraj, A Soumaré, JC Bis… - JAMA Network …, 2024 - jamanetwork.com
Importance Vascular disease is a treatable contributor to dementia risk, but the role of
specific markers remains unclear, making prevention strategies uncertain. Objective To …

Polygenic Susceptibility to Hypertension and Cognitive Performance in Middle-aged Persons Without Stroke or Dementia

CA Rivier, N Szejko, D Renedo, RB Noche, JN Acosta… - Neurology, 2023 - AAN Enterprises
Background and Objectives Mounting evidence indicates that hypertension leads to a higher
risk of dementia. Hypertension is a highly heritable trait, and a higher polygenic …

[HTML][HTML] Computer-aided extraction of select MRI markers of cerebral small vessel disease: A systematic review

J Jiang, D Wang, Y Song, PS Sachdev, W Wen - Neuroimage, 2022 - Elsevier
Cerebral small vessel disease (CSVD) is a major vascular contributor to cognitive
impairment in ageing, including dementias. Imaging remains the most promising method for …