Approved nanomedicine against diseases

Y Jia, Y Jiang, Y He, W Zhang, J Zou, KT Magar… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases.
Nanotechnology represents one of the most effective approaches in elevating a drug's …

Multifunctional nanoparticle-mediated combining therapy for human diseases

X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

Lipid nanoparticle-mediated lymph node–targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response

J Chen, Z Ye, C Huang, M Qiu… - Proceedings of the …, 2022 - National Acad Sciences
The targeted delivery of messenger RNA (mRNA) to desired organs remains a great
challenge for in vivo applications of mRNA technology. For mRNA vaccines, the targeted …

Oral nanotherapeutics of andrographolide/carbon monoxide donor for synergistically anti-inflammatory and pro-resolving treatment of ulcerative colitis

Y Zhou, M Yang, X Yan, L Zhang, N Lu… - … Applied Materials & …, 2023 - ACS Publications
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology affecting
the colon and rectum. Current therapeutics are focused on suppressing inflammation but are …

[HTML][HTML] Current research trends of nanomedicines

Q Liu, J Zou, Z Chen, W He, W Wu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

[HTML][HTML] Liposomes and liposome-like nanoparticles: From anti-fungal infection to the COVID-19 pandemic treatment

Y He, W Zhang, Q Xiao, L Fan, D Huang… - Asian Journal of …, 2022 - Elsevier
The liposome is the first nanomedicine transformed into the market and applied to human
patients. Since then, such phospholipid bilayer vesicles have undergone technological …

Recent advances in lipid nanoparticles for delivery of mRNA

L Yang, L Gong, P Wang, X Zhao, F Zhao, Z Zhang… - Pharmaceutics, 2022 - mdpi.com
Messenger RNA (mRNA), which is composed of ribonucleotides that carry genetic
information and direct protein synthesis, is transcribed from a strand of DNA as a template …

Recent advances in kaolinite nanoclay as drug carrier for bioapplications: a review

Q Wu, J Liao, H Yang - Advanced Science, 2023 - Wiley Online Library
Advanced functional two‐dimensional (2D) nanomaterials offer unique advantages in drug
delivery systems for disease treatment. Kaolinite (Kaol), a nanoclay mineral, is a natural 2D …

[HTML][HTML] Sequential delivery of PD-1/PD-L1 blockade peptide and IDO inhibitor for immunosuppressive microenvironment remodeling via an MMP-2 responsive dual …

C Hu, Y Song, Y Zhang, S He, X Liu, X Yang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Intelligent responsive drug delivery system opens up new avenues for realizing safer and
more effective combination immunotherapy. Herein, a kind of tumor cascade-targeted …

[HTML][HTML] Lipid carriers for mRNA delivery

W Zhang, Y Jiang, Y He, H Boucetta, J Wu… - … Pharmaceutica Sinica B, 2023 - Elsevier
Messenger RNA (mRNA) is the template for protein biosynthesis and is emerging as an
essential active molecule to combat various diseases, including viral infection and cancer …