Maintaining attention for more than a few seconds is essential for mastering everyday life.
Yet, our ability to stay focused on a particular task is limited, resulting in well-known …

Rationale and objective Empirical studies indicate that nicotine enhances some aspects of
attention and cognition, suggesting a role in the maintenance of tobacco dependence. The …

Despite intensive scientific investigation and public health imperatives, drug addiction
treatment outcomes have not significantly improved in more than 50years. Non-invasive …

A growing body of preclinical evidence indicates that addiction to cocaine is associated with
neuroadaptive changes in frontostriatal brain systems. Human studies in cocaine-dependent …

Background: The many putative beneficial effects of the polyphenol resveratrol include an
ability to bolster endogenous antioxidant defenses, modulate nitric oxide synthesis, and …

Historically, ACh has been implicated in learning and short-term memory functions.
However, more recent studies have provided support for a role of cortical ACh in attentional …

Rationale Nicotine has been shown in a variety of studies in humans and experimental
animals to improve cognitive function. Nicotinic treatments are being developed as …

The behavioural and cognitive effects of nicotine in schizophrenia have received much
interest in recent years. The rate of smoking in patients with schizophrenia is estimated to be …

Tobacco smoking among patients with psychiatric disease is more common than in the
general population, due to complex neurobiological, psychological, and …

BACKGROUND: In adult animals and humans, nicotine can produce short-term cognitive
enhancement and, in some cases, neuroprotection. Recent work in animals, however …