Status and challenges of plant-anticancer compounds in cancer treatment
Nowadays, cancer is one of the deadliest diseases in the world, which has been estimated
to cause 9.9 million deaths in 2020. Conventional treatments for cancer commonly involve …
to cause 9.9 million deaths in 2020. Conventional treatments for cancer commonly involve …
The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer
Aberrant expression and activity of G proteins and G-protein-coupled receptors (GPCRs) are
frequently associated with tumorigenesis. Deep sequencing studies show that 4.2% of …
frequently associated with tumorigenesis. Deep sequencing studies show that 4.2% of …
[HTML][HTML] Safety and efficacy of nivolumab monotherapy in recurrent or metastatic cervical, vaginal, or vulvar carcinoma: results from the phase I/II CheckMate 358 trial
Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal,
or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial - PMC Back to Top …
or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial - PMC Back to Top …
Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas
JC Nault, S Datta, S Imbeaud, A Franconi, M Mallet… - Nature …, 2015 - nature.com
Hepatocellular carcinomas (HCCs) are liver tumors related to various etiologies, including
alcohol intake and infection with hepatitis B (HBV) or C (HCV) virus. Additional risk factors …
alcohol intake and infection with hepatitis B (HBV) or C (HCV) virus. Additional risk factors …
Novel insights into G protein and G protein-coupled receptor signaling in cancer
M O'Hayre, MS Degese, JS Gutkind - Current opinion in cell biology, 2014 - Elsevier
G protein-coupled receptors (GPCRs) play a central role in signal transmission, thereby
controlling many facets of cellular function. Overwhelming evidence now implicates GPCRs …
controlling many facets of cellular function. Overwhelming evidence now implicates GPCRs …
Carcinogenesis mechanisms of Fusobacterium nucleatum
Transformed cells of cancers may be related to stromal cells, immune cells, and some
bacteria such as Fusobacterium nucleatum. This review aimed to evaluate carcinogenesis …
bacteria such as Fusobacterium nucleatum. This review aimed to evaluate carcinogenesis …
[HTML][HTML] The chick chorioallantoic membrane (CAM) as a versatile patient-derived xenograft (PDX) platform for precision medicine and preclinical research
LC DeBord, RR Pathak, M Villaneuva… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Patient-derived xenografts (PDX) are an increasingly valuable tool in oncology, providing
biologically faithful models of many different cancer types, and potential platforms for the …
biologically faithful models of many different cancer types, and potential platforms for the …
Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq
Elucidation of tumor-DNA virus associations in many cancer types has enhanced our
knowledge of fundamental oncogenesis mechanisms and provided a basis for cancer …
knowledge of fundamental oncogenesis mechanisms and provided a basis for cancer …
The role of gammaherpesviruses in cancer pathogenesis
Worldwide, one fifth of cancers in the population are associated with viral infections. Among
them, gammaherpesvirus, specifically HHV4 (EBV) and HHV8 (KSHV), are two oncogenic …
them, gammaherpesvirus, specifically HHV4 (EBV) and HHV8 (KSHV), are two oncogenic …
Oral microbiota and cancer
JH Meurman - Journal of oral microbiology, 2010 - Taylor & Francis
Inflammation caused by infections may be the most important preventable cause of cancer in
general. However, in the oral cavity the role of microbiota in carcinogenesis is not known …
general. However, in the oral cavity the role of microbiota in carcinogenesis is not known …