[HTML][HTML] SRplot: A free online platform for data visualization and graphing

D Tang, M Chen, X Huang, G Zhang, L Zeng… - PLoS …, 2023 - journals.plos.org
Graphics are widely used to provide summarization of complex data in scientific
publications. Although there are many tools available for drawing graphics, their use is …

Quantitative protein biomarker panels: a path to improved clinical practice through proteomics

J Hartl, F Kurth, K Kappert, D Horst… - EMBO Molecular …, 2023 - embopress.org
The utilisation of protein biomarker panels, rather than individual protein biomarkers, offers a
more comprehensive representation of human physiology. It thus has the potential to …

[HTML][HTML] Proteomics-driven noninvasive screening of circulating serum protein panels for the early diagnosis of hepatocellular carcinoma

X Xing, L Cai, J Ouyang, F Wang, Z Li, M Liu… - Nature …, 2023 - nature.com
Early diagnosis of hepatocellular carcinoma (HCC) lacks highly sensitive and specific
protein biomarkers. Here, we describe a staged mass spectrometry (MS)-based discovery …

High-throughput intact Glycopeptide quantification strategy with targeted-MS (HTiGQs-target) reveals site-specific IgG N-glycopeptides as biomarkers for hepatic …

X Liu, B Fu, J Chen, Z Sun, D Zheng, Z Li, B Gu… - Carbohydrate …, 2024 - Elsevier
Liver disease is one of the leading causes of global mortality, and identifying biomarkers for
diagnosing the progression of liver diseases is crucial for improving its outcomes. Targeted …

Plasma metabolic signatures for intracranial aneurysm and its rupture identified by pseudotargeted metabolomics

K Sun, X Zhang, X Li, X Li, S Su, Y Luo, H Tian… - Clinica Chimica …, 2023 - Elsevier
Background and aims The vital metabolic signatures for IA risk stratification and its potential
biological underpinnings remain elusive. Our study aimed to develop an early diagnosis …

Molecular magnetic resonance imaging of aneurysmal inflammation using a redox active iron complex

RM King, MJ Gounis, EJ Schmidt, A Leporati… - Investigative …, 2023 - journals.lww.com
Objectives Inflammation plays a key role in driving brain aneurysmal instability and rupture,
but clinical tools to noninvasively differentiate between inflamed and stable aneurysms are …

Proteomic Analysis Identifies GSN as a Noninvasive Circulating Serum Biomarker for Predicting Early Recurrence of Hepatocellular Carcinoma

E Hu, T Yang, L Cai, J Ouyang, F Wang… - Journal of Proteome …, 2024 - ACS Publications
Hepatocellular carcinoma (HCC) is susceptible to early recurrence, but it lacks effective
predictive biomarkers. In this study, we retrospectively selected 179 individuals as a …

[HTML][HTML] Risk stratification of papillary thyroid cancers using multidimensional machine learning

Y Li, F Wu, W Ge, Y Zhang, Y Hu, L Zhao… - … Journal of Surgery, 2024 - journals.lww.com
Background: Papillary thyroid cancer (PTC) is one of the most common endocrine
malignancies with different risk levels. However, preoperative risk assessment of PTC is still …

Gut Microbiota, Metabolites, Circulating Cytokines and Growth Factors, Plasma Proteins, and Risk of Intracranial Aneurysms: A Two‐Sample Mendelian …

A Maimaiti, Z Xie, M Turhon, A Abulizi… - Acta Neurologica …, 2024 - Wiley Online Library
Background: Increasing evidence implicates the gut microbiota, metabolites, circulating
cytokines and growth factors, and plasma proteins as potential susceptibility factors for …

Glypican-1 may be a plasma biomarker for predicting the rupture of small intracranial aneurysms.

C Wang, Y Han, X Li - Journal of Proteomics, 2024 - Elsevier
Currently, there are no effective methods for predicting the rupture of asymptomatic small
intracranial aneurysms (IA)(< 7 mm). In this study the aim was to identify early warning …