Recent development of microfluidic biosensors for the analysis of antibiotic residues

X Wang, Y Xie, L Lin - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
The large-scale use of antibiotics and the resulting drug residues poses a significant threat
to global human health. Waste discharge and biological chain transmission are closely …

Engineering Single-Component Antibacterial Anti-inflammatory Polyitaconate-Based Hydrogel for Promoting Methicillin-Resistant Staphylococcus aureus-Infected …

M Wang, T Li, J Tian, L Zhang, Y Wang, S Li, B Lei… - ACS …, 2023 - ACS Publications
Hydrogel wound dressings play a crucial role in promoting the healing of drug-resistant
bacterially infected wounds. However, their clinical application often faces challenges such …

Biomimetic multifunctional hybrid sponge via enzymatic cross-linking to accelerate infected burn wound healing

J Li, X Sun, J Dai, J Yang, L Li, Z Zhang, J Guo… - International Journal of …, 2023 - Elsevier
Preparing sponge dressings with stable wet adhesion remains difficult in wound repair,
especially in burn wounds with bleeding and large amounts of exudate. In this work, a …

The efficacy of anti‐proteolytic peptide R7I in intestinal inflammation, function, microbiota, and metabolites by multi‐omics analysis in murine bacterial enteritis

T Sun, X Liu, Y Su, Z Wang, B Cheng… - Bioengineering & …, 2023 - Wiley Online Library
Increased antibiotic resistance poses a major limitation in tackling inflammatory bowel
disease and presents a large challenge for global health care. Antimicrobial peptides …

Gelatinase-responsive biodegradable targeted microneedle patch for abscess wound treatment of S. aureus infection

XL Lei, K Cheng, YG Hu, Y Li, XL Hou, F Zhang… - International Journal of …, 2023 - Elsevier
Abscess wound caused by bacterial infection is usually difficult to heal, thus greatly affect
people's quality of life. In this study, a biodegradable drug-loaded microneedle patch (MN) is …

Glycopeptides: Insights Towards Resistance, Clinical Pharmacokinetics and Pharmacodynamics

ST Paritala, G Gandhi, K Agrawal, P Sengupta… - Indian Journal of …, 2024 - Springer
Glycopeptides have emerged as life-saving therapeutics in treating various gram-positive
bacterial infections. Vancomycin being the first therapeutically approved glycopeptide has …

Polymyxin b conjugates with bio-inspired synthetic polymers of different nature

A Dvoretckaia, T Egorova, A Dzhuzha, M Levit… - International Journal of …, 2023 - mdpi.com
The emergence and growth of bacterial resistance to antibiotics poses an enormous threat
to humanity in the future. In this regard, the discovery of new antibiotics and the improvement …

Pharmacokinetics and Nephrotoxicity of Polymyxin MRX-8 in Rats: A Novel Agent against Resistant Gram-Negative Bacteria

X Qu, C Guo, S Liu, X Li, L Xi, X Liu, J Zhang - Antibiotics, 2024 - mdpi.com
MRX-8 is a novel polymyxin for carbapenem-resistant Gram-negative infections that has
been recently evaluated in Phase I clinical trials. Herein, its pharmacokinetics (PK) and …

The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures

B Antunes, C Zanchi, PR Johnston, B Maron… - PLoS …, 2024 - journals.plos.org
The prevalence of antibiotic-resistant pathogens has become a major threat to public health,
requiring swift initiatives for discovering new strategies to control bacterial infections. Hence …

Enhanced adsorption of tetracycline using modified second pyrolysis oil-based drill cutting ash

H Yang, Z Ding, Y Zou, Y Liu, Y Zhang, S Xia - Environmental Science and …, 2022 - Springer
In this work, second pyrolysis oil-based drill cutting ash (OBDCA-sp) was modified using
NaOH and cetyltrimethylammonium bromide (CTAB), respectively. The modified OBDCA-sp …