[HTML][HTML] NF-κB inhibitors in treatment and prevention of lung cancer

RR Rasmi, KM Sakthivel… - Biomedicine & …, 2020 - Elsevier
Intracellular signalling pathways have provided excellent resource for drug development
particularly in the development of cancer therapeutics. A wide variety of malignancies …

The role of mesenchymal stem cells in radiation-induced lung fibrosis

M Zanoni, M Cortesi, A Zamagni, A Tesei - International journal of …, 2019 - mdpi.com
Radiation therapy is one of the most important treatment modalities for thoracic tumors.
Despite significant advances in radiation techniques, radiation-induced lung injury (RILI) still …

Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1

X Li, L Duan, S Yuan, X Zhuang, T Qiao, J He - Journal of inflammation, 2019 - Springer
Background Radiation-induced lung fibrosis (RILF) is a severe and life-threatening
complication of thoracic radiotherapy. Cell death is the key issue in RILF. Ferroptosis is a …

[HTML][HTML] Role of ferroptosis in the process of acute radiation-induced lung injury in mice

X Li, X Zhuang, T Qiao - Biochemical and biophysical research …, 2019 - Elsevier
Radiation-induced lung injury (RILI) is one of the most common and fatal complications of
thoracic radiotherapy. Cell death is the critical point in RILI. Ferroptosis is discovered …

Pirfenidone modulates macrophage polarization and ameliorates radiation‐induced lung fibrosis by inhibiting the TGF‐β1/Smad3 pathway

H Ying, M Fang, QQ Hang, Y Chen… - Journal of cellular …, 2021 - Wiley Online Library
Radiation‐induced lung injury (RILI) mainly contributes to the complications of thoracic
radiotherapy. RILI can be divided into radiation pneumonia (RP) and radiation‐induced lung …

Concise review: therapeutic potential of the mesenchymal stem cell derived secretome and extracellular vesicles for radiation-induced lung injury: progress and …

S Xu, C Liu, HL Ji - Stem Cells Translational Medicine, 2019 - academic.oup.com
Radiation-induced lung injury (RILI) is a common complication in radiotherapy of thoracic
tumors and limits the therapeutic dose of radiation that can be given to effectively control …

LXA4-FPR2 signaling regulates radiation-induced pulmonary fibrosis via crosstalk with TGF-β/Smad signaling

H Kim, SH Park, SY Han, YS Lee, J Cho… - Cell Death & Disease, 2020 - nature.com
Radiation therapy is an important modality in the treatment of lung cancer, but it can lead to
radiation pneumonitis, and eventually radiation fibrosis. To date, only few available drugs …

Glycyrrhizin mitigates radiation‐induced acute lung injury by inhibiting the HMGB1/TLR4 signalling pathway

L Zheng, Q Zhu, C Xu, M Li, H Li, PQ Yi… - Journal of cellular …, 2020 - Wiley Online Library
Radiation‐induced lung injury (RILI) is the major complication of thoracic radiation therapy,
and no effective treatment is available. This study explored the role of high‐mobility group …

Mesenchymal stem cells in radiation-induced lung injury: From mechanisms to therapeutic potential

G Hou, J Li, W Liu, J Wei, Y Xin, X Jiang - Frontiers in Cell and …, 2022 - frontiersin.org
Radiotherapy (RT) is an effective treatment option for multiple thoracic malignant tumors,
including lung cancers, thymic cancers, and tracheal cancers. Radiation-induced lung injury …

Rational Design of Nanomaterials for Various Radiation‐Induced Diseases Prevention and Treatment

J Xie, M Zhao, C Wang, Y Yong, Z Gu… - Advanced Healthcare …, 2021 - Wiley Online Library
Radiation treatments often unfavorably damage neighboring healthy organs and cause a
series of radiation sequelae, such as radiation‐induced hematopoietic system diseases …