[HTML][HTML] Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration

TR Stankiewicz, DA Linseman - Frontiers in cellular neuroscience, 2014 - frontiersin.org
The Rho family of GTPases belongs to the Ras superfamily of low molecular weight (∼ 21
kDa) guanine nucleotide binding proteins. The most extensively studied members are RhoA …

The dendritic tree and brain disorders

VA Kulkarni, BL Firestein - Molecular and Cellular Neuroscience, 2012 - Elsevier
Dendrite morphogenesis is a complex but well-orchestrated process and includes the
development of dendritic branches, forming characteristic dendrite arbors, and dendritic …

[图书][B] Fundamental neuroscience

L Squire, D Berg, FE Bloom, S Du Lac, A Ghosh… - 2012 - books.google.com
The fourth edition of Fundamental Neuroscience reinvents itself as an engrossing and
comprehensive presentation of the discipline of neuroscience, from molecules to cognition …

The role of the Rho GTPases in neuronal development

EE Govek, SE Newey, L Van Aelst - Genes & development, 2005 - genesdev.cshlp.org
Our brain serves as a center for cognitive function and neurons within the brain relay and
store information about our surroundings and experiences. Modulation of this complex …

Rho and Ras GTPases in axon growth, guidance, and branching

A Hall, G Lalli - Cold Spring Harbor perspectives in …, 2010 - cshperspectives.cshlp.org
The establishment of precise neuronal cell morphology provides the foundation for all
aspects of neurobiology. During development, axons emerge from cell bodies after an initial …

Novel bacterial ADP-ribosylating toxins: structure and function

NC Simon, K Aktories, JT Barbieri - Nature Reviews Microbiology, 2014 - nature.com
Bacterial ADP-ribosyltransferase toxins (bARTTs) transfer ADP-ribose to eukaryotic proteins
to promote bacterial pathogenesis. In this Review, we use prototype bARTTs, such as …

Kctd13 deletion reduces synaptic transmission via increased RhoA

CO Escamilla, I Filonova, AK Walker, ZX Xuan… - Nature, 2017 - nature.com
Copy-number variants of chromosome 16 region 16p11. 2 are linked to neuropsychiatric
disorders,,,,, and are among the most prevalent in autism spectrum disorders,,. Of many …

Rho GTPases, dendritic structure, and mental retardation

SE Newey, V Velamoor, EE Govek… - Journal of …, 2005 - Wiley Online Library
A consistent feature of neurons in patients with mental retardation is abnormal dendritic
structure and/or alterations in dendritic spine morphology. Deficits in the regulation of the …

Clostridial toxins

MR Popoff, P Bouvet - Future microbiology, 2009 - Future Medicine
Clostridia produce the highest number of toxins of any type of bacteria and are involved in
severe diseases in humans and other animals. Most of the clostridial toxins are pore-forming …

[HTML][HTML] PTBP1 knockdown promotes neural differentiation of glioblastoma cells through UNC5B receptor

K Wang, S Pan, P Zhao, L Liu, Z Chen, H Bao… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Cell reprogramming technology is utilized to prevent cancer progression by
transforming cells into terminally differentiated, non-proliferating states. Polypyrimidine tract …