Over the past decade the number and variety of protein post-translational modifications that
have been detected and characterized in bacteria have rapidly increased. Most post …

Networks of molecular regulators are often the primary objects of focus in the study of gene
regulation, with the machinery of protein synthesis tacitly relegated to the background …

Hydrogels with high mechanical strength and injectability have attracted extensive attention
in biomedical and tissue engineering. However, endowing a hydrogel with both properties is …

The gut microbiota affects many important host functions, including the immune response
and the nervous system. However, while substantial progress has been made in growing …

As a major etiological agent of human dental caries, Streptococcus mutans resides primarily
in biofilms that form on the tooth surfaces, also known as dental plaque. In addition to caries …

Insulin resistance is the primary pathophysiology underlying metabolic syndrome and type 2
diabetes,. Previous metagenomic studies have described the characteristics of gut …

Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

Although obesity occurs in most of the patients with type 2 diabetes (T2D), a fraction of
patients with T2D are underweight or have normal weight. Several studies have linked the …

Clostridioides difficile is a bacterial pathogen that causes a range of clinical disease from
mild to moderate diarrhea, pseudomembranous colitis, and toxic megacolon. Typically, C …

Beyond fuelling cellular activities with building blocks and energy, metabolism also
integrates environmental conditions into intracellular signals. The underlying regulatory …