Neural correlates of consciousness: progress and problems

C Koch, M Massimini, M Boly, G Tononi - Nature reviews neuroscience, 2016 - nature.com
There have been a number of advances in the search for the neural correlates of
consciousness—the minimum neural mechanisms sufficient for any one specific conscious …

Therapeutic interventions in patients with prolonged disorders of consciousness

A Thibaut, N Schiff, J Giacino, S Laureys… - The Lancet …, 2019 - thelancet.com
The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …

Stratification of unresponsive patients by an independently validated index of brain complexity

S Casarotto, A Comanducci, M Rosanova… - Annals of …, 2016 - Wiley Online Library
Objective Validating objective, brain‐based indices of consciousness in behaviorally
unresponsive patients represents a challenge due to the impossibility of obtaining …

[HTML][HTML] Basal forebrain control of wakefulness and cortical rhythms

C Anaclet, NP Pedersen, LL Ferrari, A Venner… - Nature …, 2015 - nature.com
Wakefulness, along with fast cortical rhythms and associated cognition, depend on the basal
forebrain (BF). BF cholinergic cell loss in dementia and the sedative effect of anti-cholinergic …

Neural correlates of consciousness in patients who have emerged from a minimally conscious state: a cross-sectional multimodal imaging study

C Di Perri, MA Bahri, E Amico, A Thibaut… - The Lancet …, 2016 - thelancet.com
Background Between pathologically impaired consciousness and normal consciousness
exists a scarcely researched transition zone, referred to as emergence from minimally …

[HTML][HTML] The input-output relationship of the cholinergic basal forebrain

MR Gielow, L Zaborszky - Cell reports, 2017 - cell.com
Basal forebrain cholinergic neurons influence cortical state, plasticity, learning, and
attention. They collectively innervate the entire cerebral cortex, differentially controlling …

The neuroethics of disorders of consciousness: a brief history of evolving ideas

MJ Young, YG Bodien, JT Giacino, JJ Fins, RD Truog… - Brain, 2021 - academic.oup.com
Neuroethical questions raised by recent advances in the diagnosis and treatment of
disorders of consciousness are rapidly expanding, increasingly relevant and yet …

[HTML][HTML] The curing coma campaign: framing initial scientific challenges—proceedings of the first curing coma campaign scientific advisory council meeting

JJ Provencio, JC Hemphill, J Claassen, BL Edlow… - Neurocritical care, 2020 - Springer
Coma and disordered consciousness are common manifestations of acute neurological
conditions and are among the most pervasive and challenging aspects of treatment in …

[HTML][HTML] Sleep-like cortical OFF-periods disrupt causality and complexity in the brain of unresponsive wakefulness syndrome patients

M Rosanova, M Fecchio, S Casarotto, S Sarasso… - Nature …, 2018 - nature.com
Unresponsive wakefulness syndrome (UWS) patients may retain intact portions of the
thalamocortical system that are spontaneously active and reactive to sensory stimuli but fail …

[HTML][HTML] Mechanisms underlying disorders of consciousness: bridging gaps to move toward an integrated translational science

AI Luppi, J Cain, LRB Spindler, UJ Górska, D Toker… - Neurocritical care, 2021 - Springer
Aim In order to successfully detect, classify, prognosticate, and develop targeted therapies
for patients with disorders of consciousness (DOC), it is crucial to improve our mechanistic …