[HTML][HTML] Novel pharmacological approaches in abdominal aortic aneurysm

L Puertas-Umbert, R Almendra-Pegueros… - Clinical …, 2023 - portlandpress.com
Abdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health
issue with an unmet medical need for therapy. This disease is featured by a progressive …

[HTML][HTML] T cells in abdominal aortic aneurysm: immunomodulation and clinical application

W Gong, Y Tian, L Li - Frontiers in Immunology, 2023 - frontiersin.org
Abdominal aortic aneurysm (AAA) is characterized by inflammatory cell infiltration,
extracellular matrix (ECM) degradation, and vascular smooth muscle cell (SMC) dysfunction …

Optimization of nano-microparticle size and shape on wall-interaction: a human case study on an abdominal aortic aneurysm

S Ebrahimi, I Mirafzal, A Rahbary… - Engineering …, 2023 - Taylor & Francis
Spherical nano-microcarriers generally perform targeted delivery of drugs to blood vessels
with lesions. Recently, some studies have shown the importance of the non-spherical nature …

[HTML][HTML] Administration of an antibody against apoptosis inhibitor of macrophage prevents aortic aneurysm progression in mice

T Fujii, A Yamawaki-Ogata, S Terazawa, Y Narita… - Scientific Reports, 2024 - nature.com
Apoptosis inhibitor of macrophage (AIM) is known to induce apoptosis resistance in
macrophages and to exacerbate chronic inflammation, leading to arteriosclerosis. The role …

Chemokine Receptor 2 Is A Theranostic Biomarker for Abdominal Aortic Aneurysms

Y Liu, SB Elizondo, S Sastriques-Dunlop, L Detering… - medRxiv, 2023 - medrxiv.org
Abdominal aortic aneurysm (AAA) is a degenerative vascular disease impacting aging
populations with a high mortality upon rupture. There are no effective medical therapies to …

[PDF][PDF] A REVIEW OF ABDOMINAL AORTIC ANEURYSMS: RISK FACTORS, SCREENING, PHARMACOLOGICAL APPROACH.

DA BRIE, A JIANU, R POPESCU, T MARCOVICI… - …, 2024 - farmaciajournal.com
Most patients with abdominal aortic aneurysm (AAA) are asymptomatic, being diagnosed
during an imaging evaluation for other symptoms. AAA rupture is an emergency, being one …

[PDF][PDF] Drug therapy for abdominal aortic aneurysms with special reference to diabetes mellitus

T Kawada - International Journal of Cardiology, 2023 - Elsevier
Li et al. reviewed several pharmacological treatments in patients with asymptomatic
abdominal aortic aneurysms (AAA), having diameters of 30–50 mm [1]. Especially …