Leveraging immuno-fluorescence data to reduce pathologist annotation requirements in lung tumor segmentation using deep learning

H Mehrabian, J Brodbeck, P Lyu, E Vaquero… - Scientific Reports, 2024 - nature.com
The main bottleneck in training a robust tumor segmentation algorithm for non-small cell
lung cancer (NSCLC) on H&E is generating sufficient ground truth annotations. Various …

Sampling, composition, and biological effects of Mexico City airborne particulate matter from multiple periods

M Santibáñez-Andrade… - Science of The Total …, 2024 - Elsevier
Air pollution is a worldwide environmental problem with an impact on human health.
Particulate matter of ten micrometers or less aerodynamic diameter (PM 10) as well as its …

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-small-cell lung cancer: a systematic review and meta-analysis of …

W Deng, K Wang, Y Jiang, D Li, C Bao, J Luo, L Liu… - BMJ open, 2022 - bmjopen.bmj.com
Objectives Combination treatment with erlotinib plus bevacizumab has the potential to
become a standard treatment regimen for patients with epidermal growth factor receptor …

Role of circular RNAs in the diagnosis, regulation of drug resistance and prognosis of lung cancer

C Sang, D Rao, C Wu, Y Xia, M Si… - Oncology …, 2022 - spandidos-publications.com
Lung cancer is one of the most common malignant tumors in China and is the highest cause
of mortality among male and female patients, both in urban and rural areas. A subset of …

Targeted exome sequencing identifies mutational landscape in a cohort of 1500 Chinese patients with non-small cell lung carcinoma (NSCLC)

Y Zhou, W Zheng, Q Zeng, Y Ye, C Wang, C Fang… - Human genomics, 2021 - Springer
Background Non-small cell lung carcinoma (NSCLC) is one of the most common human
cancers, comprising approximately 80–85% of all lung carcinomas. An estimated incidence …

Circ_0060967 facilitates proliferation, migration, and invasion of non-small-cell lung cancer cells by sponging miR-660-3p/UBN2

Z Zhu, K Zhang, M Lou, J Tong, Q Wu, J Lu… - Molecular and Cellular …, 2023 - Springer
Growing evidence has implied that circular RNAs (circRNAs) are involved in multiple tumors
progression. This study firstly uncovered the function of circ_0060967 in non-small-cell lung …

Revolutionizing Lung Cancer Treatment with Smart Pulmonary Drug Delivery Nanosystems

O Gamal, AT Agamey, Z Amr, IM El-Sherbiny - Journal of Drug Delivery …, 2024 - Elsevier
The worldwide rise in lung cancer cases has placed a heavy socio-economic strain on the
healthcare system, particularly in developing nations. Lung cancer typically presents a …

PLEK2 promotes the proliferation and migration of non-small cell lung cancer cells in a BRD4-dependent manner

T Cai, W Yao, L Qiu, AR Zhu, Z Shi, Y Du - Molecular Biology Reports, 2022 - Springer
Background It has been reported that Pleckstrin 2 (PLEK2) acts as an oncogene in non-
small cell lung cancer (NSCLC). Bromodomain containing protein 4 (BRD4), an important …

Identification and prognostic biomarkers among ZDHHC4/12/18/24, and APT2 in lung adenocarcinoma

J Bian, W Xiong, Z Yang, M Li, D Song, Y Zhang… - Scientific Reports, 2024 - nature.com
S-palmitoylases and S-depalmitoylases are differentially expressed in various cancers and
several malignant tumors and show a strong prognostic ability. Notwithstanding, the …

High expression of AlkB homolog 5 suppresses the progression of non‐small cell lung cancer by facilitating ferroptosis through m6A demethylation of SLC7A11

Z Huang, G Lin, Y Hong, L Weng, K Zhu… - Environmental …, 2024 - Wiley Online Library
Objective Non‐small cell lung cancer (NSCLC) is a prevailing LC characterized by poor
outcomes. AlkB homolog 5 (ALKBH5) functions as a tumor suppressor in several cancers …