Methods We searched all original papers and reviews about the molecular mechanisms of
ferroptosis in antioxidant systems using PubMed to November 2021. The search terms used …

Low back pain (LBP) is a leading cause of labour loss and disability worldwide, and it also
imposes a severe economic burden on patients and society. Among symptomatic LBP …

A variety of programmed cell death types have been shown to participate in the loss of
smooth muscle cells (SMCs) during the development of aortic dissection (AD), but it is still …

Reactive oxygen species (ROS)/reactive nitrogen species (RNS)-mediated ferroptosis
becomes a novel effective target for anti-cancer treatment. In the present study, we tested the …

Breast cancer has become a serious threat to women's health. Cancer progression is mainly
derived from resistance to apoptosis induced by procedures or therapies. Therefore, new …

It has been wildly reported that microplastics (MPs) can adsorb heavy metals and act as
carriers for their transport into organisms. However, the combined toxicity of MPs and heavy …

Ferroptosis is triggered by a chain of intracellular labile iron‐dependent peroxidation of cell
membrane phospholipids. Ferroptosis is important not only as a cause of ischaemic and …

Atherosclerosis (AS) is a major cause of cardiovascular diseases such as coronary heart
disease, heart failure and stroke. Abnormal lipid metabolism, oxidative stress and …

Oxidative stress and AKT serine-threonine kinase (AKT) are responsible for regulating
several cell functions of cancer cells. Several natural products modulate both oxidative …

Increasing studies have reported that intervertebral disc degeneration (IVDD) is the main
contributor and independent risk factor for low back pain (LBP), it would be, therefore …