[HTML][HTML] Anti-aging effect of phlorizin on D-galactose–induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation …

H Chen, L Dong, X Chen, C Ding, M Hao, X Peng… - Experimental …, 2022 - Elsevier
Aging is an inevitable and complicated process involving many physiological changes.
Screening of natural biologically active anti-aging substances is a current research hotspot …

[HTML][HTML] Improving translatability of spinal cord injury research by including age as a demographic variable

AN Stewart, LAT Jones, JC Gensel - Frontiers in Cellular …, 2022 - frontiersin.org
Pre-clinical and clinical spinal cord injury (SCI) studies differ in study design, particularly in
the demographic characteristics of the chosen population. In clinical study design, criteria …

Intestinal dopamine receptor D2 is required for neuroprotection against 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced dopaminergic neurodegeneration

H Peng, S Yu, Y Zhang, Y Yin, J Zhou - Neuroscience Bulletin, 2022 - Springer
A wealth of evidence has suggested that gastrointestinal dysfunction is associated with the
onset and progression of Parkinson's disease (PD). However, the mechanisms underlying …

Progress Report on the Spinal Cord Rehabilitation Research Initiatives Based on Registered Clinical Studies From 2000 to 2022

JC Furlan, DT Furlan… - American Journal of …, 2023 - journals.lww.com
The current rehabilitation therapy protocols for management of individuals with spinal cord
injury or disease aim to maximize restoration of remaining function and minimize secondary …

[HTML][HTML] Age at onset of spinal cord injury is associated with increased inpatient care needs, reduced independence at discharge and a higher risk of …

P Keusen, T Vuilliomenet, M Friedli… - Journal of Rehabilitation …, 2023 - ncbi.nlm.nih.gov
AGE AT ONSET OF SPINAL CORD INJURY IS ASSOCIATED WITH INCREASED INPATIENT
CARE NEEDS, REDUCED INDEPENDENCE AT DISCHARGE AND A HIGHER RISK OF …

Effects of age on survival and neurological recovery of individuals following acute traumatic spinal cord injury

JC Furlan - Spinal Cord, 2022 - nature.com
Study design Retrospective cohort study. Objectives To evaluate the effects of older age at
the time of injury on the individuals' survival and neurological recovery within the first year …

Sex-related discrepancies in the access to optimal care and outcomes after traumatic spinal cord injury: a retrospective cohort study using data from a Canadian …

JC Furlan, T Shen, D Kurban - Archives of Physical Medicine and …, 2023 - Elsevier
Objective To compare males and females who were stratified into subgroups corresponding
to premenopausal, perimenopausal, and postmenopausal ages, regarding access to …

Racial and Ethnical Discrepancies and Similarities in the Epidemiology, Survival, and Neurological Outcomes After Acute Traumatic Spinal Cord Injury: A …

JC Furlan - Topics in Spinal Cord Injury Rehabilitation, 2023 - meridian.allenpress.com
Background Little is known about the impact of race/ethnicity on the clinical and neurological
outcomes after acute traumatic spinal cord injury (tSCI). Objectives This study examined the …

Concomitant traumatic brain injury as a determinant of survival, and neurological and functional outcomes after traumatic spinal cord injury: A retrospective cohort …

JC Furlan - PM&R, 2024 - Wiley Online Library
Background Although concomitant traumatic brain injury (TBI) is not infrequently associated
with spinal cord injury (SCI), there is relatively scarce information about the effects of …

Epitranscriptomic analysis of m6A methylome in rats after lumbosacral nerve root avulsion

Z Zhou, L Zhu - Epigenomics, 2022 - Taylor & Francis
Background: N6-methyladenosine (m6A) is the most prevalent modification in mRNAs but its
role in lumbosacral nerve root avulsion (LSRA) remains elusive. Materials & methods: Mettl3 …