[HTML][HTML] Geographic distribution, clinical epidemiology and genetic diversity of the human oncogenic retrovirus HTLV-1 in Africa, the world's largest endemic area

A Gessain, JL Ramassamy, PV Afonso… - Frontiers in …, 2023 - frontiersin.org
The African continent is considered the largest high endemic area for the oncogenic
retrovirus HTLV-1 with an estimated two to five million infected individuals. However, data on …

[HTML][HTML] Risk factors associated with HTLV-1 vertical transmission in Brazil: longer breastfeeding, higher maternal proviral load and previous HTLV-1-infected offspring

AM Paiva, T Assone, MEJ Haziot, J Smid… - Scientific reports, 2018 - nature.com
HTLV-1 is transmitted primarily either through sexual intercourse or from mother to child. The
mother/child pairs were classified as seroconcordant or serodiscordant. We analyzed …

[HTML][HTML] Re-emergence of human T-lymphotropic viruses in West Africa

NCJS Anyanwu, EE Ella, A Ohwofasa… - Brazilian journal of …, 2018 - SciELO Brasil
Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals
worldwide via the same transmission routes as HIV. With the aim of exposing the possible re …

The prevalence of human T‐lymphotropic virus type 1 & 2 (HTLV‐1/2) in South African blood donors

M Vermeulen, W Sykes, C Coleman, B Custer… - Vox …, 2019 - Wiley Online Library
Background and objectives Donated blood is not currently screened for human T‐cell
lymphotropic virus (HTLV) in South Africa. Several small studies have detected HTLV‐1 in …

Comparing toxicity of galbanic acid, auraptene and umbelliprenin on adult T-cell leukaemia-lymphoma in normoxia and hypoxia

S Goudarzi, FB Rassouli, D Kahrizi… - Cellular and Molecular …, 2022 - cellmolbiol.org
Natural coumarins are valuable agents that induce anticancer effects and/or enhance
sensitivity to therapeutic modalities. Galbanic acid (GBA), auraptene (AUR) and …

[HTML][HTML] Risk factors for HTLV-1 infection in Central Africa: A rural population-based survey in Gabon

DD Djuicy, A Mouinga-Ondémé, O Cassar… - PLOS neglected …, 2018 - journals.plos.org
Background Human T-Lymphotropic Virus type 1 (HTLV-1) is a human oncoretrovirus that
infects at least 5 to 10 million people worldwide and is associated with severe diseases …

[HTML][HTML] HTLV-1 and HIV-2 infection are associated with increased mortality in a rural West African community

C van Tienen, M Schim van der Loeff, I Peterson… - Plos one, 2011 - journals.plos.org
Background Survival of people with HIV-2 and HTLV-1 infection is better than that of HIV-1
infected people, but long-term follow-up data are rare. We compared mortality rates of HIV-1 …

[HTML][HTML] Point-of-care system for HTLV-1 proviral load quantification by digital mediator displacement LAMP

L Becherer, JF Hess, S Frischmann, M Bakheit… - Micromachines, 2021 - mdpi.com
This paper presents a universal point-of-care system for fully automated quantification of
human T-cell lymphotropic virus type 1 (HTLV-1) proviral load, including genomic RNA …

[HTML][HTML] Molecular epidemiology of endemic human T-lymphotropic virus type 1 in a rural community in Guinea-Bissau

C van Tienen, TI de Silva, LCJ Alcantara… - PLoS neglected …, 2012 - journals.plos.org
Background Human T-Lymphotropic Virus Type 1 (HTLV-1) infection causes lethal adult T-
cell leukemia (ATL) and severely debilitating HTLV-associated myelopathy/tropical spastic …

HTLV prevalence is no longer following the decreasing HIV prevalence–20 years of retroviral surveillance in Guinea-Bissau, West Africa

MM Jensen, JS Olesen, B Kjerulff, S Byberg… - Acta Tropica, 2019 - Elsevier
Abstract Background The HIV-2 and HTLV-1 prevalences in Bissau have followed similar
trends in surveys from 1996 and 2006 with HTLV-1 prevalences of 3.6% and 2.3 …