Osteosarcoma is the most common primary malignant bone tumor mainly occurred in
children and adolescence, and chemotherapy is limited for the side effects and development …

Intelligent responsive drug delivery system opens up new avenues for realizing safer and
more effective combination immunotherapy. Herein, a kind of tumor cascade-targeted …

Nanoformulations with advantages in drug delivery, safety and pharmacodynamics have
been booming as a promising strategy for cancer therapy. However, the traditional …

Liposomes are nano-sized lipid-based vesicles widely studied for their drug delivery
capabilities. Compared to standard carries they exhibit better properties such as improved …

Highlights•This article first focuses on the progress of stimuli-responsive theranostics based
on lanthanide-doped upconversion nanoparticles (UCNPs) that activate diagnostic signals …

Liposomes, with their flexible physicochemical and biophysical properties, continue to be
studied as an important potential a critical drug delivery system. Liposomes have overcome …

Proteolysis Targeting Chimera (PROTAC) technology represents a promising new approach
for target protein degradation using a cellular ubiquitin-proteasome system. Recently, we …

Therapeutic targeting of the immune system, including chimeric antigen receptor-T cell
therapy, immune checkpoint blockade therapy, neoantigen vaccines, and small molecule …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide,
with high rates of recurrence and death. Surgical resection and ablation therapy have limited …

Liposomes are currently part of the most reputed carriers for various molecular species, from
small and simple to large and complex molecules. Since their discovery, liposomes have …