Current problems and future avenues in proteoliposome research
AM Amati, S Graf, S Deutschmann… - Biochemical Society …, 2020 - portlandpress.com
Membrane proteins (MPs) are the gatekeepers between different biological compartments
separated by lipid bilayers. Being receptors, channels, transporters, or primary pumps, they …
separated by lipid bilayers. Being receptors, channels, transporters, or primary pumps, they …
Challenges and opportunities in delivering oral peptides and proteins
H Peng, J Wang, J Chen, Y Peng, X Wang… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Rapid advances in bioengineering enable the use of complex proteins as
therapeutic agents to treat diseases. Compared with conventional small molecule drugs …
therapeutic agents to treat diseases. Compared with conventional small molecule drugs …
[HTML][HTML] The next-generation DNA vaccine platforms and delivery systems: Advances, challenges and prospects
B Lu, JM Lim, B Yu, S Song, P Neeli… - Frontiers in …, 2024 - frontiersin.org
Vaccines have proven effective in the treatment and prevention of numerous diseases.
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …
[HTML][HTML] Natural compounds in liposomal nanoformulations of potential clinical application in glioblastoma
L Piwowarczyk, DT Mlynarczyk, V Krajka-Kuźniak… - Cancers, 2022 - mdpi.com
Simple Summary Glioma is a type of cancer that is the most common primary brain tumor in
adults. The prognosis is often unfavorable despite early detection and treatment. Therefore …
adults. The prognosis is often unfavorable despite early detection and treatment. Therefore …
Analyzing liposomal drug delivery systems in three-dimensional cell culture models using MALDI imaging mass spectrometry
JK Lukowski, EM Weaver, AB Hummon - Analytical chemistry, 2017 - ACS Publications
Cancer chemotherapeutics often fail to reach all diseased cells. To help solve this problem,
researchers are investigating novel drug delivery systems. Liposomes are an attractive …
researchers are investigating novel drug delivery systems. Liposomes are an attractive …
[HTML][HTML] Application of lipid-based nanocarriers for antitubercular drug delivery: a review
The antimicrobial drugs currently used for the management of tuberculosis (TB) exhibit poor
bioavailability that necessitates prolonged treatment regimens and high dosing frequency to …
bioavailability that necessitates prolonged treatment regimens and high dosing frequency to …
Recent advancements in liposome-targeting strategies for the treatment of gliomas: a systematic review
J Li, T Tan, L Zhao, M Liu, Y You, Y Zeng… - ACS Applied Bio …, 2020 - ACS Publications
Malignant tumors represent some of the most intractable diseases that endanger human
health. A glioma is a tumor of the central nervous system that is characterized by severe …
health. A glioma is a tumor of the central nervous system that is characterized by severe …
[HTML][HTML] An insight into the risk factors of brain tumors and their therapeutic interventions
Brain tumors are an abnormal growth of cells in the brain, also known as multifactorial
groups of neoplasm. Incidence rates of brain tumors increase rapidly, and it has become a …
groups of neoplasm. Incidence rates of brain tumors increase rapidly, and it has become a …
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzyme cleavable linker mediated effective intracellular delivery of siRNA
Z Yu, X Zhang, X Pei, W Cao, J Ye, J Wang… - International Journal of …, 2021 - Elsevier
The tissue-specific targeted delivery and efficient cellular uptake of siRNAs are the main
obstacles to their clinical application. Antibody-siRNA-conjugates (ARCs) can deliver siRNA …
obstacles to their clinical application. Antibody-siRNA-conjugates (ARCs) can deliver siRNA …
[HTML][HTML] Traditional Chinese medicine combined with hepatic targeted drug delivery systems: A new strategy for the treatment of liver diseases
Z Ma, B Zhang, Y Fan, M Wang, D Kebebe, J Li… - Biomedicine & …, 2019 - Elsevier
Liver diseases are clinically common and present a substantial public health issue. Many of
the currently available drugs for the treatment of liver diseases suffer from limitations that …
the currently available drugs for the treatment of liver diseases suffer from limitations that …