Delivery of antisense oligonucleotides using multi-layer coated gold nanoparticles to methicillin-resistant S. aureus for combinatorial treatment

MJ Beha, JS Ryu, YS Kim, HJ Chung - Materials Science and Engineering …, 2021 - Elsevier
The spread of multidrug-resistant (MDR) bacterial infections has become a serious global
threat. We introduce multi-layer coated gold nanoparticles (MLGNPs) delivering antisense …

[HTML][HTML] A novel estrogen-targeted PEGylated liposome co-delivery oxaliplatin and paclitaxel for the treatment of ovarian cancer

Y Xie, Z Ren, H Chen, H Tang, M Zhu, Z Lv… - Biomedicine & …, 2023 - Elsevier
Ovarian cancer is the second cause of death among gynecological malignancies. In this
study, we designed a novel estrogen-targeted PEGylated liposome loaded with oxaliplatin …

[HTML][HTML] The Flavonoid components of Scutellaria baicalensis: Biopharmaceutical properties and their improvement using nanoformulation techniques

J Wang, X Feng, Z Li, Y Liu, W Yang… - Current topics in …, 2023 - ncbi.nlm.nih.gov
Scutellaria baicalensis georgi, known as “Huangqin” in its dried root form, is a herb widely
used in traditional Chinese medicine for “clearing away heat, removing dampness, purging …

[HTML][HTML] Xeroderma pigmentosum: general aspects and management

M Piccione, A Belloni Fortina, G Ferri… - Journal of Personalized …, 2021 - mdpi.com
Xeroderma Pigmentosum (XP) is a rare genetic syndrome with a defective DNA nucleotide
excision repair. It is characterized by (i) an extreme sensitivity to ultraviolet (UV)-induced …

Advanced nanoparticles, the hallmark of targeted drug delivery for osteosarcoma-an updated review

S Ashique, M Faiyazuddin, O Afzal, S Gowri… - Journal of Drug Delivery …, 2023 - Elsevier
Osteosarcoma could be a sort of threatening tumor that starts in a bone and spreads to
adjoining bone cells. Among the different sorts of bone malignancies, osteosarcoma is the …

Proteomic exploration of endocytosis of framework nucleic acids

T Tian, C Zhang, J Li, Y Liu, Y Wang, X Ke, C Fan… - Small, 2021 - Wiley Online Library
Efficient cell internalization of framework nucleic acid nanostructures free of transfection
agents provides new opportunities for developing biocompatible and intelligent nanoprobes …

[HTML][HTML] Liposome-encapsulated tobramycin and IDR-1018 peptide mediated biofilm disruption and enhanced antimicrobial activity against Pseudomonas aeruginosa

NM Alzahrani, RY Booq, AM Aldossary, AA Bakr… - Pharmaceutics, 2022 - mdpi.com
The inadequate eradication of pulmonary infections and chronic inflammation are significant
complications in cystic fibrosis (CF) patients, who usually suffer from persistent and frequent …

[HTML][HTML] Review of recently used techniques and materials to improve the efficiency of orally administered proteins/peptides

YHEY Ibrahim, G Regdon, EI Hamedelniel… - DARU Journal of …, 2020 - Springer
Objectives The main objective of present review is to explore and evaluate the effectiveness
of recently developed methods to improve the bioavailability of orally administered …

Dual-targeting liposomes with active recognition of GLUT5 and αvβ3 for triple-negative breast cancer

Y Pu, H Zhang, Y Peng, Q Fu, Q Yue, Y Zhao… - European journal of …, 2019 - Elsevier
At present, chemo-and radiotherapies remain to be the mainstream methods for treating
triple-negative breast cancer (TNBC), which is known for poor prognosis and high rate of …

Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes …

MM El Sayed, H Takata, T Shimizu… - Journal of Controlled …, 2020 - Elsevier
The accelerated blood clearance (ABC) phenomenon, caused in large degree via in vivo
anti-PEG IgM production, is one of obstacles for development of PEGylated liposome and …