Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal malignancies and is
characterized by a unique tumor microenvironment (TME) consisting of an abundant stromal …

Pancreatic cancer is one of the leading causes of cancer death worldwide. Its high mortality
rate has remained unchanged for years. Radiotherapy and surgery are considered standard …

Contemporary analyses focused on a limited number of clinical and molecular biomarkers
have been unable to accurately predict clinical outcomes in pancreatic ductal …

Background The prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is
poor and selection of patients for surgery is challenging. This study examined the impact of a …

The mortality and morbidity rates of pancreatic cancer are high because of its extremely
invasive and metastatic nature. Its lack of symptoms, late diagnosis and chemo–resistance …

Irisin, a recently identified myokine that is released from skeletal muscle following exercise,
regulates body weight and influences various metabolic diseases such as obesity and …

Cancer is a pathology that impacts in a profound manner all over the world. The election
strategy against cancer often uses chemotherapy and radiotherapy, which, more often than …

Introduction nab-Paclitaxel plus gemcitabine (nab-P+ G) and FOLFIRINOX (FFX) are among
the most common first-line (1L) therapies for metastatic adenocarcinoma of the pancreas …

Pancreatic cancer (PC) is one of the most common causes of cancer-related death. The
underlying mechanism of PC is not completely understood at present. Studies in recent …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers in the United
States with a five-year survival rate of 7.2% for all stages. Although surgical resection is the …