Chimerism analysis has become an important tool for the peri-transplant surveillance of
engraftment. It offers the possibility to realize impending graft rejection and can serve as an …

Nonmyeloablative allogeneic stem cell transplantation has recently been explored as a
safer alternative to conventional high-dose transplant regimens. Although a high incidence …

Purpose We recently reported that children with acute leukemias who show increasing
mixed chimerism (MC) after allogeneic stem-cell transplantation have a significantly …

Sequential analysis of chimerism after allogeneic blood stem cell transplantation (BSCT)
has been shown to be predictive for graft failure and relapse. We have explored the impact …

Bone marrow engraftment (BME) analysis of allogeneic bone marrow transplant (allo-BMT)
patients can detect residual recipient cells that survive the conditioning regimen. The results …

Previous studies have shown that children with acute myeloid leukemia (AML) who
developed mixed chimerism (MC) were at high risk for relapse after allogeneic stem-cell …

The monitoring of chimerism by PCR has become a routine diagnostic approach in patients
after allogeneic bone marrow or peripheral blood stem cell transplantation. Nevertheless, a …

The success of allogeneic stem cell transplantation (allo-SCT) in children is mainly affected
by relapse or graft rejection. We have recently shown in a study of 55 patients with acute …

One of the major complications after allogeneic stem cell transplantation (SCT) in patients
with malignant disease is a high frequency of relapse. We have prospectively analyzed the …

Little data are available on the relative merits of chimerism and minimal residual disease
(MRD) monitoring for relapse prediction after allogeneic hematopoietic stem cell …