Recent advances in the biology of mammalian pigmentation are reviewed. The multicellular
epidermal melanin unit (melanocyte and associated pool of keratinocytes) rather than the …

The quinone intermediates resulting from tyrosinase-mediated oxidation of tyrosine were
evaluated as sulfhydryl reagent inhibitors of purified calf thymus DNA polymerase α in order …

The substrates and intermediates involved in the conversion of tyrosine or 3, 4-
dihydroxyphenylalanine into melanin by autooxidation, or tyrosinases (monophenol …

Tyrosine hydroxylase, dopa oxidase, and peroxidase activities were studied in soluble
fractions of B16 melanoma tumor homogenates by polyacrylamide gel disc electrophoresis …

To characterize how structural properties are related to the morphological differentiation of
melanosomes, two forms of melanosomes, commonly seen in mammals, were isolated from …

In the melanocyte, tyrosinase is known as the dey enzyme for melanin formation. Purified
tyrosinase protein was prepared that was capable of oxidizing tyrosine. The localization of …

Ultrastructural studies, and cytochemical and biochemical determinations of tyrosinase
activity were conducted on the pigment epithelium of albino and xanthic goldfish eyes. In …

Abstract Tyrosinase (EC 1.14. 18.1) was purified from regenerating chicken feathers. Most of
the enzyme activity was in the insoluble fraction, which was solubilized with 0.5% sodium …

The improved method presented here for localizing monophenoloxidase activity of
tyrosinase (EC 1.14. 18.1.) after electrophoresis is based on the transfer of electrons from …

ACTH and corticosterone altered tyrosinase activity in the B-16, S-91 and Harding-Passey
melanomas but did not evoke any changes in peroxidase activity. Tyrosinase activity, but not …