Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with disease
Transcription factor EB (TFEB), a member of the MiT/TFE family of basic helix-loop-helix
leucine zipper transcription factors, is an established central regulator of the …
leucine zipper transcription factors, is an established central regulator of the …
Targeting autophagy in ischemic stroke: from molecular mechanisms to clinical therapeutics
A Ajoolabady, S Wang, G Kroemer… - Pharmacology & …, 2021 - Elsevier
Stroke constitutes the second leading cause of death and a major cause of disability
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …
Amyloid-type protein aggregation and prion-like properties of amyloids
This review will focus on the process of amyloid-type protein aggregation. Amyloid fibrils are
an important hallmark of protein misfolding diseases and therefore have been investigated …
an important hallmark of protein misfolding diseases and therefore have been investigated …
Psycho-neuroendocrine-immune interactions in COVID-19: potential impacts on mental health
Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
[HTML][HTML] Signal pathways in the treatment of Alzheimer's disease with traditional Chinese medicine
MR Ding, YJ Qu, B Hu, HM An - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
Natural compounds and autophagy: allies against neurodegeneration
A Stacchiotti, G Corsetti - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Prolonging the healthy life span and limiting neurological illness are imperative goals in
gerontology. Age-related neurodegeneration is progressive and leads to severe diseases …
gerontology. Age-related neurodegeneration is progressive and leads to severe diseases …
cGAS-STING pathway aggravates early cerebral ischemia-reperfusion injury in mice by activating NCOA4-mediated ferritinophagy
B Li, W Wang, Y Li, S Wang, H Liu, Z Xia, W Gao… - Experimental …, 2023 - Elsevier
Stroke patients are often complicated by cerebral ischemia-reperfusion injury (CIRI) after the
restoration of cerebral perfusion, and how to prevent CIRI at an early stage has received …
restoration of cerebral perfusion, and how to prevent CIRI at an early stage has received …
New visions on natural products and cancer therapy: autophagy and related regulatory pathways
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …
paying attention to medicinal applications of natural products. There are several …
Selective autophagy as a therapeutic target for neurological diseases
W Xu, U Ocak, L Gao, S Tu, CJ Lenahan… - Cellular and Molecular …, 2021 - Springer
The neurological diseases primarily include acute injuries, chronic neurodegeneration, and
others (eg, infectious diseases of the central nervous system). Autophagy is a housekeeping …
others (eg, infectious diseases of the central nervous system). Autophagy is a housekeeping …