Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with disease

A Tan, R Prasad, C Lee, E Jho - Cell Death & Differentiation, 2022 - nature.com
Transcription factor EB (TFEB), a member of the MiT/TFE family of basic helix-loop-helix
leucine zipper transcription factors, is an established central regulator of the …

Targeting autophagy in ischemic stroke: from molecular mechanisms to clinical therapeutics

A Ajoolabady, S Wang, G Kroemer… - Pharmacology & …, 2021 - Elsevier
Stroke constitutes the second leading cause of death and a major cause of disability
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …

Amyloid-type protein aggregation and prion-like properties of amyloids

D Willbold, B Strodel, GF Schröder, W Hoyer… - Chemical …, 2021 - ACS Publications
This review will focus on the process of amyloid-type protein aggregation. Amyloid fibrils are
an important hallmark of protein misfolding diseases and therefore have been investigated …

Psycho-neuroendocrine-immune interactions in COVID-19: potential impacts on mental health

Í Raony, CS de Figueiredo, P Pandolfo… - Frontiers in …, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Signal pathways in the treatment of Alzheimer's disease with traditional Chinese medicine

MR Ding, YJ Qu, B Hu, HM An - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …

Natural compounds and autophagy: allies against neurodegeneration

A Stacchiotti, G Corsetti - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Prolonging the healthy life span and limiting neurological illness are imperative goals in
gerontology. Age-related neurodegeneration is progressive and leads to severe diseases …

cGAS-STING pathway aggravates early cerebral ischemia-reperfusion injury in mice by activating NCOA4-mediated ferritinophagy

B Li, W Wang, Y Li, S Wang, H Liu, Z Xia, W Gao… - Experimental …, 2023 - Elsevier
Stroke patients are often complicated by cerebral ischemia-reperfusion injury (CIRI) after the
restoration of cerebral perfusion, and how to prevent CIRI at an early stage has received …

New visions on natural products and cancer therapy: autophagy and related regulatory pathways

A Martelli, M Omrani, M Zarghooni, V Citi, S Brogi… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …

Selective autophagy as a therapeutic target for neurological diseases

W Xu, U Ocak, L Gao, S Tu, CJ Lenahan… - Cellular and Molecular …, 2021 - Springer
The neurological diseases primarily include acute injuries, chronic neurodegeneration, and
others (eg, infectious diseases of the central nervous system). Autophagy is a housekeeping …