Extracellular matrix remodeling and cardiac fibrosis

L Li, Q Zhao, W Kong - Matrix biology, 2018 - Elsevier
Cardiac fibrosis, characterized by excessive deposition of extracellular matrix (ECM)
proteins in the myocardium, distorts the architecture of the myocardium, facilitates the …

Participation of women in clinical trials supporting FDA approval of cardiovascular drugs

PE Scott, EF Unger, MR Jenkins, MR Southworth… - Journal of the American …, 2018 - jacc.org
Background: Concerns exist that women are underrepresented in trials of cardiovascular
medications. Objectives: The authors sought to examine women's participation and the …

[HTML][HTML] Discovery and refinement of loci associated with lipid levels

CJ Willer, EM Schmidt, S Sengupta, GM Peloso… - Nature …, 2013 - ncbi.nlm.nih.gov
Low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol,
triglycerides, and total cholesterol are heritable, modifiable, risk factors for coronary artery …

Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial

Y Huo, J Li, X Qin, Y Huang, X Wang, RF Gottesman… - Jama, 2015 - jamanetwork.com
Importance Uncertainty remains about the efficacy of folic acid therapy for the primary
prevention of stroke because of limited and inconsistent data. Objective To test the primary …

[HTML][HTML] Atualização da diretriz de prevenção cardiovascular da Sociedade Brasileira de Cardiologia-2019

DB Précoma, GMM Oliveira, AF Simão… - Arquivos Brasileiros …, 2019 - SciELO Brasil
Níveis de evidência Nível A Dados obtidos a partir de múltiplos estudos randomizados de
bom porte, concordantes e/ou de meta-análise robusta de estudos clínicos randomizados …

Coronary artery disease: from mechanism to clinical practice

C Shao, J Wang, J Tian, Y Tang - Coronary Artery Disease: Therapeutics …, 2020 - Springer
In most developed countries, coronary artery disease (CAD), mostly caused by
atherosclerosis of coronary arteries, is one of the primary causes of death. From 1990s to …

2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart …

CW Yancy, M Jessup, B Bozkurt, J Butler, DE Casey Jr… - Circulation, 2013 - Am Heart Assoc
The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted through October 2011 and includes selected …

Pathophysiology of native coronary, vein graft, and in-stent atherosclerosis

K Yahagi, FD Kolodgie, F Otsuka, AV Finn… - Nature Reviews …, 2016 - nature.com
Plaque rupture, usually of a precursor lesion known as a'vulnerable plaque'or'thin-cap
fibroatheroma', is the leading cause of thrombosis. Less-frequent aetiologies of coronary …

2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart …

PT O'Gara, FG Kushner, DD Ascheim, DE Casey… - Journal of the American …, 2013 - jacc.org
1.1. Methodology and Evidence Review The recommendations listed in this document are,
whenever possible, evidence based. The current document constitutes a full revision and …

Comparative effectiveness of transitional care services in patients discharged from the hospital with heart failure: a systematic review and network meta‐analysis

HGC Van Spall, T Rahman, O Mytton… - European journal of …, 2017 - Wiley Online Library
Aims To compare the effectiveness of transitional care services in decreasing all‐cause
death and all‐cause readmissions following hospitalization for heart failure (HF). Methods …