Metabolomics in neonatology: fact or fiction?

V Fanos, J Van den Anker, A Noto, M Mussap… - Seminars in Fetal and …, 2013 - Elsevier
The newest 'omics' science is metabolomics, the latest offspring of genomics, considered the
most innovative of the 'omics' sciences. Metabolomics, also called the 'new clinical …

[HTML][HTML] Omics-based biomarkers in the diagnosis of diabetes

WZ Gan, V Ramachandran, CSY Lim… - Journal of Basic and …, 2020 - degruyter.com
Diabetes mellitus (DM) is a group of metabolic diseases related to the dysfunction of insulin,
causing hyperglycaemia and life-threatening complications. Current early screening and …

NGAL and metabolomics: the single biomarker to reveal the metabolome alterations in kidney injury

A Noto, F Cibecchini, V Fanos… - BioMed research …, 2013 - Wiley Online Library
Conditions affecting kidney structure and function can be considered acute or chronic,
depending on their duration. Acute kidney injury (AKI) is one of a number of acute kidney …

Preprocessing of NMR metabolomics data

LR Euceda, GF Giskeødegård… - Scandinavian journal of …, 2015 - Taylor & Francis
Metabolomics involves the large scale analysis of metabolites and thus, provides
information regarding cellular processes in a biological sample. Independently of the …

Emerging biomarkers and metabolomics for assessing toxic nephropathy and acute kidney injury (AKI) in neonatology

M Mussap, A Noto, V Fanos… - BioMed research …, 2014 - Wiley Online Library
Identification of novel drug‐induced toxic nephropathy and acute kidney injury (AKI)
biomarkers has been designated as a top priority by the American Society of Nephrology …

Biomarkers in transplantation—proteomics and metabolomics

U Christians, J Klawitter, J Klawitter - Therapeutic drug monitoring, 2016 - journals.lww.com
Modern multianalyte “omics” technologies allow for the identification of molecular signatures
that confer significantly more information than measurement of a single parameter as …

A high-performance liquid chromatography–tandem mass spectrometry–based targeted metabolomics kidney dysfunction marker panel in human urine

J Klepacki, J Klawitter, J Klawitter, JM Thurman… - Clinica Chimica …, 2015 - Elsevier
Background Previous studies have examined and documented fluctuations in urine
metabolites in response to disease processes and drug toxicity affecting glomerular filtration …

Biomarkers of immunosuppressant organ toxicity after transplantation: status, concepts and misconceptions

U Christians, J Klawitter, J Klawitter… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: A major challenge in transplantation is improving long-term organ transplant
and patient survival. Immunosuppressants protect the transplant organ from alloimmune …

Proteomics and metabolomics in renal transplantation‐quo vadis?

R Bohra, J Klepacki, J Klawitter, J Klawitter… - Transplant …, 2013 - Wiley Online Library
The improvement of long‐term transplant organ and patient survival remains a critical
challenge following kidney transplantation. Proteomics and biochemical profiling …

Pharma-metabolomics in neonatology: is it a dream or a fact?

V Fanos, L Barberini, R Antonucci… - Current Pharmaceutical …, 2012 - ingentaconnect.com
The 'omics' technologies represent analytical approaches that have a holistic view on
molecules such as genes, transcripts, proteins and metabolites constituting a cell, tissue or …