[HTML][HTML] The role of antioxidants in the interplay between oxidative stress and senescence
Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …
The origins and evolution of sleep
Sleep is nearly ubiquitous throughout the animal kingdom, yet little is known about how
ecological factors or perturbations to the environment shape the duration and timing of …
ecological factors or perturbations to the environment shape the duration and timing of …
Melatonin and healthy aging
DP Cardinali - Vitamins and hormones, 2021 - Elsevier
Preservation of a robust circadian rhythmicity (particulsarly of the sleep/wake cycle), a
proper nutrition and adequate physical exercise are key elements for healthy aging. Aging …
proper nutrition and adequate physical exercise are key elements for healthy aging. Aging …
Meta-analysis of age and actigraphy-assessed sleep characteristics across the lifespan
Abstract Study Objectives Sleep quantity and continuity vary across the lifespan. Actigraphy
is a reliable and widely used behavioral measure of sleep in research and personal health …
is a reliable and widely used behavioral measure of sleep in research and personal health …
Circadian metabolism: from mechanisms to metabolomics and medicine
SA Brown - Trends in Endocrinology & Metabolism, 2016 - cell.com
The circadian clock directs nearly all aspects of diurnal physiology, including metabolism.
Current research identifies several major axes by which it exerts these effects, including …
Current research identifies several major axes by which it exerts these effects, including …
[HTML][HTML] Sleep in older adults and its possible relations with COVID-19
GN Pires, IA Ishikura, SD Xavier, C Petrella… - Frontiers in aging …, 2021 - frontiersin.org
Since the beginning of the COVID-19 pandemic, older adults have been found to be a highly
vulnerable group, with a higher prevalence of severe cases and negative outcomes …
vulnerable group, with a higher prevalence of severe cases and negative outcomes …
Factors involved in sleep efficiency: a population-based study of community-dwelling elderly persons
S Desjardins, S Lapierre, C Hudon, A Desgagné - Sleep, 2019 - academic.oup.com
Abstract Study Objectives Research indicates that sleep efficiency below 80% substantially
increases mortality risk in elderly persons. The aim of this study was to identify factors that …
increases mortality risk in elderly persons. The aim of this study was to identify factors that …
Overnight worsening of emotional distress indicates maladaptive sleep in insomnia
Abstract Study Objectives Mechanisms underlying the distress of hyperarousal in people
with insomnia remain enigmatic. We investigated whether insomnia impedes the overnight …
with insomnia remain enigmatic. We investigated whether insomnia impedes the overnight …
[HTML][HTML] Sex differences in frailty among older adults
By definition, aging is a natural, gradual and continuous process. On the other hand, frailty
reflects the increase in vulnerability to stressors and shortens the time without disease …
reflects the increase in vulnerability to stressors and shortens the time without disease …
[HTML][HTML] Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy
A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …
memory loss and cognitive decline. Although substantial research has been conducted to …