HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta …

RK Gupta, J Gregson, N Parkin… - The Lancet infectious …, 2018 - thelancet.com
Background Pretreatment drug resistance in people initiating or re-initiating antiretroviral
therapy (ART) containing non-nucleoside reverse transcriptase inhibitors (NNRTIs) might …

[PDF][PDF] Update on HIV-1 diversity in Africa: a decade in review

RW Lihana, D Ssemwanga, A Abimiku, N Ndembi - Aids Rev, 2012 - researchgate.net
Background: HIV-1 strains have diversified extensively through mutation and recombination
since their initial transmission to human beings many decades ago in Central Africa in the …

HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: a multicentre observational study

RL Hamers, CL Wallis, C Kityo, M Siwale… - The Lancet infectious …, 2011 - thelancet.com
Background There are few data on the epidemiology of primary HIV-1 drug resistance after
the roll-out of antiretroviral treatment (ART) in sub-Saharan Africa. We aimed to assess the …

HIV-1 drug resistance mutations: potential applications for point-of-care genotypic resistance testing

SY Rhee, MR Jordan, E Raizes, A Chua, N Parkin… - PloS one, 2015 - journals.plos.org
The increasing prevalence of acquired and transmitted HIV-1 drug resistance is an obstacle
to successful antiretroviral therapy (ART) in the low-and middle-income countries (LMICs) …

Primary drug resistance in South Africa: data from 10 years of surveys

J Manasa, D Katzenstein, S Cassol… - AIDS research and …, 2012 - liebertpub.com
HIV-1 transmitted drug resistance (TDR) could reverse the gains of antiretroviral rollout. To
ensure that current first-line therapies remain effective, TDR levels in recently infected …

Cohort profile: The PharmAccess African (PASER-M) and the TREAT Asia (TASER-M) monitoring studies to evaluate resistance—HIV drug resistance in sub-Saharan …

RL Hamers, R Oyomopito, C Kityo… - International journal …, 2012 - academic.oup.com
According to World Health Organization (WHO) estimates, 33.4 million people were infected
with the human immunodeficiency virus (HIV) type 1 globally at the end of 2008. 1 Sub …

An affordable HIV-1 drug resistance monitoring method for resource limited settings

J Manasa, S Danaviah, S Pillay, P Padayachee… - JoVE (Journal of …, 2014 - jove.com
HIV-1 drug resistance has the potential to seriously compromise the effectiveness and
impact of antiretroviral therapy (ART). As ART programs in sub-Saharan Africa continue to …

Increasing HIV-1 drug resistance between 2010 and 2012 in adults participating in population-based HIV surveillance in rural KwaZulu-Natal, South Africa

J Manasa, S Danaviah, R Lessells… - AIDS research and …, 2016 - liebertpub.com
As more human immunodeficiency virus (HIV)–infected patients access combination
antiretroviral therapy (cART), higher proportions of newly infected patients may be infected …

Prevalence and characteristics of HIV drug resistance among antiretroviral treatment (ART) experienced adolescents and young adults living with HIV in Ndola …

S Miti, R Handema, L Mulenga, JK Mwansa… - PLoS …, 2020 - journals.plos.org
Background HIV drug resistance (HIVDR) poses a threat to the HIV epidemic control in
Zambia especially in sub-populations such as the 15–24 years where there is poor …

High prevalence of HIV-1 transmitted drug resistance and factors associated with time to virological failure and viral suppression in Taiwan

SW Huang, MC Shen, WH Wang, WY Li… - Journal of …, 2022 - academic.oup.com
Background Integrase strand transfer inhibitor (InSTI)-based regimens have become the
major first-line treatment for HIV-1-infected patients in Taiwan. Transmitted drug resistance …