Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2
Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …
The biological functions and regulatory mechanisms of fatty acid binding protein 5 in various diseases
B Xu, L Chen, Y Zhan, KNS Marquez, L Zhuo… - Frontiers in cell and …, 2022 - frontiersin.org
In recent years, fatty acid binding protein 5 (FABP5), also known as fatty acid transporter,
has been widely researched with the help of modern genetic technology. Emerging …
has been widely researched with the help of modern genetic technology. Emerging …
Stem cells for treatment of liver fibrosis/cirrhosis: clinical progress and therapeutic potential
P Liu, Y Mao, Y Xie, J Wei, J Yao - Stem Cell Research & Therapy, 2022 - Springer
Cost-effective treatment strategies for liver fibrosis or cirrhosis are limited. Many clinical trials
of stem cells for liver disease shown that stem cells might be a potential therapeutic …
of stem cells for liver disease shown that stem cells might be a potential therapeutic …
The protective roles of citrus flavonoids, naringenin, and naringin on endothelial cell dysfunction in diseases
The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …
MiR-182-5p inhibits colon cancer tumorigenesis, angiogenesis, and lymphangiogenesis by directly downregulating VEGF-C
S Yan, H Wang, X Chen, C Liang, W Shang, L Wang… - Cancer letters, 2020 - Elsevier
MicroRNAs (miRNAs) are gene modulators essential for biological processes. However, the
precise functions of miRNAs in growth and development of colon cancer are still elusive. To …
precise functions of miRNAs in growth and development of colon cancer are still elusive. To …
Biology of cancer; from cellular and molecular mechanisms to developmental processes and adaptation
IG Motofei - Seminars in Cancer Biology, 2022 - Elsevier
Cancer research has been largely focused on the cellular and molecular levels of
investigation. Recent data show that not only the cell but also the extracellular matrix plays a …
investigation. Recent data show that not only the cell but also the extracellular matrix plays a …
Dissecting the roles and clinical potential of YY1 in the tumor microenvironment
MN Li, JX Wei, CN Xue, XT Zhou, SP Chen… - Frontiers in …, 2023 - frontiersin.org
Yin-Yang 1 (YY1) is a member of the GLI-Kruppel family of zinc finger proteins and plays a
vital dual biological role in cancer as an oncogene or a tumor suppressor during …
vital dual biological role in cancer as an oncogene or a tumor suppressor during …
The tubulin detyrosination cycle: function and enzymes
J Nieuwenhuis, TR Brummelkamp - Trends in cell biology, 2019 - cell.com
Microtubules are subjected to a variety of post-translational modifications (PTMs). The
combination of different α-and β-tubulin isoforms and PTMs are referred to as the tubulin …
combination of different α-and β-tubulin isoforms and PTMs are referred to as the tubulin …
Intestinal microcirculation and necrotizing enterocolitis: the vascular endothelial growth factor system
RM Bowker, X Yan, IG De Plaen - Seminars in Fetal and Neonatal Medicine, 2018 - Elsevier
Necrotizing enterocolitis (NEC), a leading cause of morbidity and mortality in preterm
neonates, is a devastating disease characterized by intestinal tissue inflammation and …
neonates, is a devastating disease characterized by intestinal tissue inflammation and …
Antisense oligonucleotides targeting angiogenic factors as potential cancer therapeutics
Cancer is one of the leading causes of death worldwide, and conventional cancer therapies
such as surgery, chemotherapy, and radiotherapy do not address the underlying molecular …
such as surgery, chemotherapy, and radiotherapy do not address the underlying molecular …