Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Background Novel compounds and more efficient treatment options are urgently needed for
the treatment of non-small cell lung cancer (NSCLC). The decoction of Sophora flavescens …

Verbena officinalis Linn. is a kind of traditional Chinese medicine, which has a long history
of application and shows good effects on neuroprotection. Therefore, we consider that V …

Three novel matrine-type alkaloids (1–3) and two unprecedented aloperine-type alkaloids (4
and 5) were isolated from the root of Sophora tonkinensis and the seeds of Sophora …

Comprehensive Summary Chemical investigation of Fritillaria verticillata Willd. led to the
isolation of eight novel isosteroidal alkaloids (1—4, 6, 9—11) and four known alkaloids (5, 7 …

The integration of a multidimensional treatment dominated by active ingredients of
traditional Chinese medicine (TCM), including enhanced chemotherapy and synergistically …

Bone metabolism is characterized by an interplay between the deposition of bone matrix
and mineralization and the resorption process. Osteoporosis is a form of systemic metabolic …

A phytochemical investigation on the alkaloid fractions of Sophora alopecuroides L. led to
the production of 11 undescribed matrine-type alkaloids, sophaloseedlines I–S (1− 11), 12 …

Drug delivery remains a challenge in the field of medicine. Current administration methods
limit the application of peptide-protein drugs. The non-injectable administration of …