Cancer poses a significant global health challenge, with predictions of increasing
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …

Hepatocellular carcinoma (HCC) is one of the most lethal malignant tumours worldwide. The
mortality-to-incidence ratio is up to 91.6% in many countries, representing the third leading …

Some studies have reported that activated ribosomes are positively associated with
malignant tumors, especially in hepatocellular carcinoma (HCC). The RNA-binding protein …

Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently prescribed
drug classes with wide therapeutic applications over the centuries. Starting from the use of …

Combination therapy has long been applied to enhance therapeutic effect and deal with the
occurrence of multi-drug resistance in cancer treatment. However, the overlapping toxicity of …

Many studies have shown that the hyperactivation of ribosome biogenesis plays essential
roles in the initiation and progression of cancers. As a ribosome assembly factor, PNO1 …

Background: Clinical studies have shown that celecoxib can significantly inhibit the
development of tumors, and basic experiments and in vitro experiments also provide a …

Clinical and experimental evidence suggested that anesthesia choice can influence cancer
progression and patients' outcomes by modulating tumor microenvironment and tumorigenic …

PNO1 has been reported to be involved in tumorigenesis, however, its role in glioma
remains unexplored. In the present study, PNO1 expression in glioma from on-line …

Background: Drug repurposing, the application of known drugs and compounds with a
primary non-oncology purpose, might be an attractive strategy to offer more effective …