Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …

The 2019 coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in …

Background Previous studies have highlighted a relationship between reduction in rate of
exacerbations with therapies containing inhaled corticosteroids (ICS) and baseline blood …

The pathology and impact of chronic obstructive pulmonary disease (COPD) results from an
abnormal inflammatory process resulting in tissue damage with ineffective repair in …

Background Sputum and blood eosinophil counts predict corticosteroid effects in COPD
patients. Bacterial infection causes increased airway neutrophilic inflammation. The …

Breathlessness, cough, and sputum production are cardinal symptoms of patients with
chronic obstructive pulmonary disease (COPD). These respiratory symptoms are routinely …

This work was supported by grant numbers R01ES023349, P30ES010126, and US EPA CR
83578501. AJB is supported by grant number 2T32GM086330. CGD is supported by grant …

Pharmacological treatment for chronic obstructive pulmonary disease (COPD) aims to
alleviate symptoms and reduce the future risk of events such as exacerbations, disease …

Introduction: Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) is a
disease phenotype that shares T helper lymphocyte cell Th1/neutrophilic/non-Type-2 …