[HTML][HTML] Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome

M Engel, D Endesfelder, B Schloter-Hai, S Kublik… - PLoS …, 2017 - journals.plos.org
Background Changes in microbial community composition in the lung of patients suffering
from moderate to severe COPD have been well documented. However, knowledge about …

[HTML][HTML] Measuring disease activity in COPD: is clinically important deterioration the answer?

D Singh, GJ Criner, I Naya, PW Jones, L Tombs… - Respiratory …, 2020 - Springer
Given the heterogeneity of chronic obstructive pulmonary disease (COPD), personalized
clinical management is key to optimizing patient outcomes. Important treatment goals …

[HTML][HTML] Circulating extracellular vesicles are associated with disease severity and interleukin-6 levels in COPD: a Pilot study

D Nieri, M Daniele, S Lombardi, E Bazzan… - Journal of Clinical …, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a complex condition in which systemic
inflammation plays a role in extrapulmonary manifestations, including cardiovascular …

[HTML][HTML] Clinical and molecular markers in COPD

I Gonçalves, MJ Guimarães, M Van Zeller, F Menezes… - Pulmonology, 2018 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease,
and there is a clinical need for validated markers and biomarkers that can contribute to the …

When to use single-inhaler triple therapy in COPD: a practical approach for primary care health care professionals

S Gaduzo, V McGovern, J Roberts… - … Journal of Chronic …, 2019 - Taylor & Francis
While single-inhaler triple therapy (SITT) devices were not available when the Global
Initiative for Chronic Obstructive Lung Disease strategy and National Institute for Health and …

A macrophage-related gene signature for identifying COPD based on bioinformatics and ex vivo experiments

Z Zhang, H Yu, Q Wang, Y Ding, Z Wang… - Journal of …, 2023 - Taylor & Francis
Background This study aims to investigate the association between immune cells and the
development of COPD, while providing a new method for the diagnosis of COPD according …

Association between dietary nutrient intake and chronic obstructive pulmonary disease severity: A nationwide population-based representative sample

T Kim, H Choi, J Kim - COPD: Journal of Chronic Obstructive …, 2020 - Taylor & Francis
Several nutrients have been suggested to protect against airway destruction via antioxidant
activity. The present study aimed to evaluate the association between disease severity and …

Can Treatable Traits Be the Approach to Addressing the Complexity and Heterogeneity of COPD?

M Cazzola, P Rogliani, F Blasi - International Journal of Chronic …, 2023 - Taylor & Francis
The complexity of COPD implies the need to identify groups of patients with similar clinical
characteristics and prognosis or treatment requirements. This is why much attention has …

Clinically important deterioration: a composite tool for managing patients with COPD

M Cazzola, MG Matera - Respiratory Medicine, 2022 - Elsevier
Clinically important deterioration (CID) is a composite tool developed to measure COPD's
progression. It is a promising concept that can improve treatment choices for COPD patients …

Clinical characteristics of COPD patients with tidal expiratory flow limitation

J Dean, U Kolsum, P Hitchen, V Gupta… - International journal of …, 2017 - Taylor & Francis
We have used impulse oscillometry to identify COPD patients with tidal expiratory flow
limitation (EFL), which is a measurement related to small airway disease. We report that …