Homocysteine and age-associated disorders

EA Ostrakhovitch, S Tabibzadeh - Ageing research reviews, 2019 - Elsevier
There are numerous theories of aging, a process which still seems inevitable. Aging leads to
cancer and multi-systemic disorders as well as chronic diseases. Decline in age-associated …

Hyperhomocysteinaemia and vascular injury: advances in mechanisms and drug targets

Y Fu, X Wang, W Kong - British journal of pharmacology, 2018 - Wiley Online Library
Homocysteine is a sulphur‐containing non‐proteinogenic amino acid.
Hyperhomocysteinaemia (HHcy), the pathogenic elevation of plasma homocysteine as a …

Alcohol and dementia–what is the link? A systematic review

C Wiegmann, I Mick, EJ Brandl, A Heinz… - Neuropsychiatric …, 2020 - Taylor & Francis
Background Dementia is a globally increasing health issue and since no cure is currently
available, prevention is crucial. The consumption of alcohol is a controversially discussed …

[PDF][PDF] Identification of peripheral blood immune infiltration signatures and construction of monocyte-associated signatures in ovarian cancer and Alzheimer's disease …

S Zhao, B Ye, H Chi, C Cheng, J Liu - Heliyon, 2023 - cell.com
Background Ovarian cancer (OC) is a common tumor of the female reproductive system,
while Alzheimer's disease (AD) is a prevalent neurodegenerative disease that primarily …

[HTML][HTML] Homocysteine and age-related central nervous system diseases: role of inflammation

A Tawfik, NM Elsherbiny, Y Zaidi… - International journal of …, 2021 - mdpi.com
Hyperhomocysteinemia (HHcy) is remarkably common among the aging population. The
relation between HHcy and the development of neurodegenerative diseases, such as …

The effect of chronic vitamin deficiency and long term very low dose exposure to 6 pesticides mixture on neurological outcomes–A real-life risk simulation approach

A Tsatsakis, NV Tyshko, AO Docea, SI Shestakova… - Toxicology letters, 2019 - Elsevier
We investigate the long-term effect of very-low dose exposure to a mixture of six pesticides
associated with hydrophilic vitamin deficiency on the neurobehavioral outcomes of rats. Two …

[HTML][HTML] A study of differential microRNA expression profile in migraine: the microMIG exploratory study

VJ Gallardo, JB Gómez-Galván, L Asskour… - The Journal of …, 2023 - Springer
Background Several studies have described potential microRNA (miRNA) biomarkers
associated with migraine, but studies are scarcely reproducible primarily due to the …

Cyclohexane extract of walnut leaves improves indices of oxidative stress, total homocysteine and lipids profiles in streptozotocin‐induced diabetic rats

G Jelodar, M Mohammadi, A Akbari… - Physiological …, 2020 - Wiley Online Library
This study aimed to evaluate the effect of two doses of cyclohexane extract of walnut leaves
on total homocysteine, lipids profiles, and indices of oxidative stress including superoxide …

[HTML][HTML] The role of DNA methylation in stroke recovery

DH Choi, IA Choi, J Lee - International Journal of Molecular Sciences, 2022 - mdpi.com
Epigenetic alterations affect the onset of ischemic stroke, brain injury after stroke, and
mechanisms of poststroke recovery. In particular, DNA methylation can be dynamically …

Epigenetic modification in alcohol use disorder and alcoholic cardiomyopathy: from pathophysiology to therapeutic opportunities

L Wu, Y Zhang, J Ren - Metabolism, 2021 - Elsevier
Alcohol consumption prompts detrimental psychological, pathophysiological and health
issues, representing one of the major causes of death worldwide. Alcohol use disorder …