Introduction Biomarkers can be useful for identifying or ruling out sepsis, identifying patients
who may benefit from specific therapies or assessing the response to therapy. Methods We …

COVID-19 is known for its magical infectivity, fast transmission and high death toll based on
the large number of infected people. From the perspective of the clinical manifestation …

Patients with critical illness, and in particular sepsis, are now recognized to undergo
unifying, pathogenic disturbances of immune function. Whilst scientific and therapeutic focus …

Growing evidence showed that inflammation response plays an important role in cancer
development and progression, and absolute lymphocyte count (ALC), absolute monocyte …

Leukocyte kinetics during the early stage acts as a prognost... : Medicine Leukocyte kinetics
during the early stage acts as a prognostic marker in patients with septic shock in intensive care …

It is known that apoptosis may play a role in the pathophysiology of amyotrophic lateral
sclerosis (ALS). Moreover, caspase-9 is implicated in the apoptosis pathway. The aim of the …

Objective Higher caspase 3 activity has been found in lymphocytes of septic patients than of
healthy controls. However, an association between serum caspase 3 levels at moment of …

Caspase-3 is the main executor of the apoptotic process. Higher serum caspase-3
concentrations in non-survivor compared to survivor septic patients have been found. The …

Mice that have been subjected to cecal ligation and puncture (CLP) have an impaired ability
to clear a subsequent Pseudomonas aeruginosa challenge compared with that of sham CLP …

Lymphocyte apoptosis is thought to have a major role in the pathophysiology of sepsis.
However, there is a disconnect between animal models of sepsis and patients with the …